2-Amino-3-(3-fluoro-4,5-dihydroxyphenyl)propanoic acid

Base Information

Chemical Name:2-Amino-3-(3-fluoro-4,5-dihydroxyphenyl)propanoic acid
CAS No.:60872-09-5
Molecular Formula:C9H10 F N O4
Molecular Weight:215.1784
Hs Code.:
NSC Number:383034

Synonyms:3,4-dihydroxy-5-fluoro-DL-phenylalanine;3,4-dihydroxy-5-fluorophenylalanine;5-fluoro-DOPA;5-fluorodopa;5-fluorodopa hydrobromide, 18F-labeled;5-fluorodopa hydrobromide, 18F-labeled, (DL)-isomer;5-fluorodopa, 3-(18)F-labeled;5-fluorodopa, 3-(18)F-labeled, (DL)-isomer;5-fluorodopa, 3-(18)F-labeled, (L)-isomer

Suppliers and Price of 2-Amino-3-(3-fluoro-4,5-dihydroxyphenyl)propanoic acid

Supply Marketing:

Business phase:: The product has achieved commercial mass production^*data from LookChem market partment

Manufacturers and distributors:

Manufacture/Brand
Chemicals and raw materials
Packaging
price

Total 8 raw suppliers

Chemical Property of 2-Amino-3-(3-fluoro-4,5-dihydroxyphenyl)propanoic acid

Chemical Property:

Vapor Pressure:4.29E-08mmHg at 25°C
Boiling Point:428.2°Cat760mmHg
Flash Point:212.8°C
Density:1.553g/cm³
XLogP3:-2.6
Hydrogen Bond Donor Count:4
Hydrogen Bond Acceptor Count:6
Rotatable Bond Count:3
Exact Mass:215.05938596
Heavy Atom Count:15
Complexity:238

Purity/Quality:: 99% ^*data from raw suppliers

Safty Information:

Pictogram(s):
Hazard Codes:

MSDS Files:: SDS file from LookChem

Useful:

Canonical SMILES:C1=C(C=C(C(=C1O)O)F)CC(C(=O)O)N

Technology Process of 2-Amino-3-(3-fluoro-4,5-dihydroxyphenyl)propanoic acid

There total 4 articles about 2-Amino-3-(3-fluoro-4,5-dihydroxyphenyl)propanoic acid which guide to synthetic route it. The literature collected by LookChem mainly comes from the sharing of users and the free literature resources found by Internet computing technology. We keep the original model of the professional version of literature to make it easier and faster for users to retrieve and use. At the same time, we analyze and calculate the most feasible synthesis route with the highest yield for your reference as below:

synthetic route:

Reference yield:

: 42877-11-2
3,4-dimethoxy-5-nitrobenzyl chloride

: 60872-09-5
2-amino-3-(3-fluoro-4,5-dihydroxyphenyl)propanoic acid

Guidance literature:: Multi-step reaction with 4 steps

1: NaOEt

2: H₂ / Pd-C / acetic acid

3: (i) NaNO₂, aq. HCl, (ii) aq. HBF₄

4: (i) (pyrolysis), (ii) H₂, aq. HBr

With hydrogen; sodium ethanolate; palladium on activated charcoal; In acetic acid;
DOI:10.1021/jm00262a026

Reference yield:

: 42877-12-3
5-(2',2'-dicarbethoxy-2'-acetamidoethyl)-2,3-dimethoxynitrobenzene

: 60872-09-5
2-amino-3-(3-fluoro-4,5-dihydroxyphenyl)propanoic acid

Guidance literature:: Multi-step reaction with 3 steps

1: H₂ / Pd-C / acetic acid

2: (i) NaNO₂, aq. HCl, (ii) aq. HBF₄

3: (i) (pyrolysis), (ii) H₂, aq. HBr

With hydrogen; palladium on activated charcoal; In acetic acid;
DOI:10.1021/jm00262a026