5-(Chloromethyl)-1,2-dimethoxy-3-nitrobenzene

Base Information

Chemical Name:5-(Chloromethyl)-1,2-dimethoxy-3-nitrobenzene
CAS No.:42877-11-2
Molecular Formula:C₉H₁₀ClNO₄
Molecular Weight:231.636
Hs Code.:
DSSTox Substance ID:DTXSID501253104

Synonyms:5-(chloromethyl)-1,2-dimethoxy-3-nitrobenzene;42877-11-2;DTXSID501253104;EN300-1964537

Suppliers and Price of 5-(Chloromethyl)-1,2-dimethoxy-3-nitrobenzene

Supply Marketing:

Business phase:: The product has achieved commercial mass production^*data from LookChem market partment

Manufacturers and distributors:

Manufacture/Brand
Chemicals and raw materials
Packaging
price

Total 1 raw suppliers

Chemical Property of 5-(Chloromethyl)-1,2-dimethoxy-3-nitrobenzene

Chemical Property:

XLogP3:2.1
Hydrogen Bond Donor Count:0
Hydrogen Bond Acceptor Count:4
Rotatable Bond Count:3
Exact Mass:231.0298355
Heavy Atom Count:15
Complexity:221

Purity/Quality:: 95% ^*data from raw suppliers

Safty Information:

Pictogram(s):
Hazard Codes:

MSDS Files:: SDS file from LookChem

Useful:

Canonical SMILES:COC1=CC(=CC(=C1OC)[N+](=O)[O-])CCl

Technology Process of 5-(Chloromethyl)-1,2-dimethoxy-3-nitrobenzene

There total 4 articles about 5-(Chloromethyl)-1,2-dimethoxy-3-nitrobenzene which guide to synthetic route it. The literature collected by LookChem mainly comes from the sharing of users and the free literature resources found by Internet computing technology. We keep the original model of the professional version of literature to make it easier and faster for users to retrieve and use. At the same time, we analyze and calculate the most feasible synthesis route with the highest yield for your reference as below:

synthetic route:

Reference yield: 93.0%

: 40681-92-3
3,4-dimethoxy-5-nitrobenzyl alcohol

: 42877-11-2
3,4-dimethoxy-5-nitrobenzyl chloride

Guidance literature:: With hydrogenchloride; for 0.666667h; Heating;
DOI:10.1016/0022-1139(93)03032-H

Reference yield:

: 22027-96-9
5-nitroveratral

: 42877-11-2
3,4-dimethoxy-5-nitrobenzyl chloride

Guidance literature:: Multi-step reaction with 2 steps

1: 90 percent / NaBH₄ / tetrahydrofuran / 1 h / 40 - 60 °C

2: 93 percent / conc. HCl / 0.67 h / Heating

With hydrogenchloride; sodium tetrahydroborate; In tetrahydrofuran;
DOI:10.1016/0022-1139(93)03032-H

Reference yield:

: 6635-20-7
isonitrovanillin

: 42877-11-2
3,4-dimethoxy-5-nitrobenzyl chloride

Guidance literature:: Multi-step reaction with 3 steps

1: (i) aq. KOH, (ii) /BRN= 635994/

2: NaBH₄ / tetrahydrofuran

3: aq. HCl

With hydrogenchloride; sodium tetrahydroborate; In tetrahydrofuran;
DOI:10.1021/jm00262a026