3,5-Difluoro-2-hydrazinopyridine

Base Information

• Chemical Name: 3,5-Difluoro-2-hydrazinopyridine
• CAS No.: 851179-06-1
• Molecular Formula: C5H5F2N3
• Molecular Weight: 145.112
• Hs Code.: 2933399990
• Mol file: 851179-06-1.mol

Synonyms:2-hydrazino-3,5-difluoropyridine;3,5-difluoro-2-hydrazinylpyridine;3,5-Difluoro-2-hydrazinopyridine;3,5-difluoro-2-pyridylhydrazine;3,5-Difluoropyridin-2-ylhydrazine;PC1973;

Chemical Property of 3,5-Difluoro-2-hydrazinopyridine

Chemical Property:

• PSA: 50.94000
• LogP: 1.41870
• Storage Temp.: 2-8°C

Purity/Quality:

99%, ^*data from raw suppliers

3,5-Difluoro-2-hydrazinopyridine ^*data from reagent suppliers

Safty Information:

• Pictogram(s): Xi
• Hazard Codes: Xi

MSDS Files:

SDS file from LookChem

Useful:

Technology Process of 3,5-Difluoro-2-hydrazinopyridine

There total 5 articles about 3,5-Difluoro-2-hydrazinopyridine which guide to synthetic route it. The literature collected by LookChem mainly comes from the sharing of users and the free literature resources found by Internet computing technology. We keep the original model of the professional version of literature to make it easier and faster for users to retrieve and use. At the same time, we analyze and calculate the most feasible synthesis route with the highest yield for your reference as below:

synthetic route:

Reference yield: 85.6%

2,3,5‐trifluoropyridine (76469-41-5) → 3,5-difluoro-2-hydrazinylpyridine (851179-06-1)

Guidance literature:

With hydrazine; In propan-1-ol; for 6h; Heating / reflux;

Reference yield: 85.0%

→ 3,5-difluoro-2-hydrazinylpyridine (851179-06-1)

Guidance literature:

Reference yield:

3,5,6-trifluoro-2-hydrazinopyridine (851179-05-0) → 3,5-difluoro-2-hydrazinylpyridine (851179-06-1)

Guidance literature:

Multi-step reaction with 2 steps

1: 65 percent / aq. CuSO₄ / Heating

2: 68 percent / hydrazine monohydrate / ethanol / 6 h / Heating

With hydrazine hydrate; copper(II) sulfate; In ethanol;

DOI:10.1002/chem.200400837

upstream raw materials:

2,3,5‐trifluoropyridine

3,5,6-trifluoro-2-hydrazinopyridine

2,3,5,6-tetrafluoropyridine

Pentafluoropyridine

Downstream raw materials:

2-bromo-3,5-difluoropyridine

3,4,5-trifluoropyridine

4-chloro-3,5-difluoro pyridine