Technology Process of 2,7-Octadienoic acid,
6-[2-[[(1,1-dimethylethyl)diphenylsilyl]oxy]ethyl]-6-ethenyl-, ethyl ester,
(2E)-
There total 8 articles about 2,7-Octadienoic acid,
6-[2-[[(1,1-dimethylethyl)diphenylsilyl]oxy]ethyl]-6-ethenyl-, ethyl ester,
(2E)- which
guide to synthetic route it.
The literature collected by LookChem mainly comes from the sharing of users and the free literature resources found by Internet computing technology. We keep the original model of the professional version of literature to make it easier and faster for users to retrieve and use. At the same time, we analyze and calculate the most feasible synthesis route with the highest yield for your reference as below:
synthetic route:
- Guidance literature:
-
Multi-step reaction with 8 steps
1.1: Red-Al / tetrahydrofuran / 3.5 h / 20 °C
1.2: 77 percent / I2 / ethyl acetate; tetrahydrofuran / 2 h / 20 °C
2.1: 88 percent / Ph3P / Pd2(dba)3*CHCl3 / dimethylformamide / 14 h / 20 °C / Stille coupling
3.1: 84 percent / Hg(OAc)2 / 18 h / 50 °C
4.1: 88 percent / i-Bu3Al / CH2Cl2 / 1 h / 20 °C
5.1: imidazole; 4-DMAP / CH2Cl2 / 0.25 h / 20 °C
6.1: TMSCl; EtOH / 0.33 h / 20 °C
7.1: 95 percent / (COCl)2; DMSO; Et3N / CH2Cl2 / 0.5 h / 20 °C
8.1: 95 percent / benzene / 1.5 h / 80 °C
With
1H-imidazole; dmap; chloro-trimethyl-silane; oxalyl dichloride; ethanol; mercury(II) diacetate; triisobutylaluminum; dimethyl sulfoxide; triethylamine; triphenylphosphine; sodium bis(2-methoxyethoxy)aluminium dihydride;
tris(dibenzylideneacetone)dipalladium(0) chloroform complex;
In
tetrahydrofuran; dichloromethane; N,N-dimethyl-formamide; benzene;
4.1: reductive Claisen rearrangement / 7.1: Swern oxidation / 8.1: Wittig reaction;
DOI:10.1055/s-2005-862388
- Guidance literature:
-
Multi-step reaction with 7 steps
1: 88 percent / Ph3P / Pd2(dba)3*CHCl3 / dimethylformamide / 14 h / 20 °C / Stille coupling
2: 84 percent / Hg(OAc)2 / 18 h / 50 °C
3: 88 percent / i-Bu3Al / CH2Cl2 / 1 h / 20 °C
4: imidazole; 4-DMAP / CH2Cl2 / 0.25 h / 20 °C
5: TMSCl; EtOH / 0.33 h / 20 °C
6: 95 percent / (COCl)2; DMSO; Et3N / CH2Cl2 / 0.5 h / 20 °C
7: 95 percent / benzene / 1.5 h / 80 °C
With
1H-imidazole; dmap; chloro-trimethyl-silane; oxalyl dichloride; ethanol; mercury(II) diacetate; triisobutylaluminum; dimethyl sulfoxide; triethylamine; triphenylphosphine;
tris(dibenzylideneacetone)dipalladium(0) chloroform complex;
In
dichloromethane; N,N-dimethyl-formamide; benzene;
3: reductive Claisen rearrangement / 6: Swern oxidation / 7: Wittig reaction;
DOI:10.1055/s-2005-862388
![4-[2-(<i>tert</i>-butyl-diphenyl-silanyloxy)-ethyl]-4-vinyl-hex-5-enal](/Databaselist/images/loading.webp)
