Quinoline, 2-pyrazinyl-

Base Information

• Chemical Name: Quinoline, 2-pyrazinyl-
• CAS No.: 64858-32-8
• Molecular Formula: C₁₃H₉N₃
• Molecular Weight: 207.235
• DSSTox Substance ID: DTXSID70215144
• Wikidata: Q83091100
• Mol file: 64858-32-8.mol

Synonyms:Quinoline, 2-pyrazinyl-;64858-32-8;2-(2-pyrazinyl)quinoline;2-(pyrazin-2-yl)quinoline;2-pyrazin-2-ylquinoline;DTXSID70215144;MFCD03617849;AKOS015992465;2W-0826

Chemical Property of Quinoline, 2-pyrazinyl-

Chemical Property:

• Vapor Pressure: 1.03E-05mmHg at 25°C
• Boiling Point: 382.6°Cat760mmHg
• Flash Point: 177.3°C
• Density: 1.229g/cm³
• XLogP3: 1.7
• Hydrogen Bond Donor Count: 0
• Hydrogen Bond Acceptor Count: 3
• Rotatable Bond Count: 1
• Exact Mass: 207.079647300
• Heavy Atom Count: 16
• Complexity: 231

Purity/Quality:

99%min ^*data from raw suppliers

Safty Information:

• Pictogram(s):  
• Hazard Codes: 

MSDS Files:

SDS file from LookChem

Useful:

• Canonical SMILES: C1=CC=C2C(=C1)C=CC(=N2)C3=NC=CN=C3

Technology Process of Quinoline, 2-pyrazinyl-

There total 2 articles about Quinoline, 2-pyrazinyl- which guide to synthetic route it. The literature collected by LookChem mainly comes from the sharing of users and the free literature resources found by Internet computing technology. We keep the original model of the professional version of literature to make it easier and faster for users to retrieve and use. At the same time, we analyze and calculate the most feasible synthesis route with the highest yield for your reference as below:

synthetic route:

Reference yield: 76.0%

2-Aminobenzyl alcohol (5344-90-1) + acetylpyrazine (22047-25-2) → 2-(2-Pyrazinyl)chinolin (64858-32-8)

Guidance literature:

With [(p-cymene)Ru(BiBzImH₂)Cl][Cl]; caesium carbonate; In tert-Amyl alcohol; at 125 ℃; for 12h;

DOI:10.1016/j.jcat.2020.12.016

Reference yield:

→ 2-(2-Pyrazinyl)chinolin (64858-32-8)

Guidance literature:

2-Methylchinolin, Formamid;

upstream raw materials:

2-Aminobenzyl alcohol

acetylpyrazine

Refernces