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Acetylpyrazine

Base Information Edit
  • Chemical Name:Acetylpyrazine
  • CAS No.:22047-25-2
  • Deprecated CAS:131922-02-6
  • Molecular Formula:C6H6N2O
  • Molecular Weight:122.126
  • Hs Code.:2933.90
  • European Community (EC) Number:244-753-5
  • NSC Number:72374
  • UNII:GR391IBU5C
  • DSSTox Substance ID:DTXSID5047085
  • Nikkaji Number:J27.905F
  • Wikipedia:Acetylpyrazine
  • Wikidata:Q15726062
  • Metabolomics Workbench ID:45162
  • ChEMBL ID:CHEMBL3188662
  • Mol file:22047-25-2.mol
Acetylpyrazine

Synonyms:2-acetylpyrazine

Suppliers and Price of Acetylpyrazine
Supply Marketing:Edit
Business phase:
The product has achieved commercial mass production*data from LookChem market partment
Manufacturers and distributors:
  • Manufacture/Brand
  • Chemicals and raw materials
  • Packaging
  • price
  • TRC
  • Acetylpyrazine
  • 5g
  • $ 55.00
  • TRC
  • Acetylpyrazine
  • 10g
  • $ 70.00
  • TCI Chemical
  • 2-Acetylpyrazine >99.0%(GC)
  • 25g
  • $ 169.00
  • TCI Chemical
  • 2-Acetylpyrazine >99.0%(GC)
  • 10g
  • $ 85.00
  • SynQuest Laboratories
  • 2-Acetylpyrazine
  • 100 g
  • $ 56.00
  • SynQuest Laboratories
  • 2-Acetylpyrazine
  • 5 g
  • $ 16.00
  • SynQuest Laboratories
  • 2-Acetylpyrazine
  • 25 g
  • $ 20.00
  • SynChem
  • Acetylpyrazine 95%
  • 10 g
  • $ 25.00
  • Sigma-Aldrich
  • 2-Acetylpyrazine ≥99%, FCC, FG
  • 5 kg
  • $ 2090.00
  • Sigma-Aldrich
  • 2-Acetylpyrazine ≥99%, FCC, FG
  • 5kg-k
  • $ 1930.00
Total 213 raw suppliers
Chemical Property of Acetylpyrazine Edit
Chemical Property:
  • Appearance/Colour:Light yellow to yellow-brownish powder 
  • Vapor Pressure:0.095mmHg at 25°C 
  • Melting Point:75-78 °C 
  • Refractive Index:1.518 
  • Boiling Point:212.9 °C at 760 mmHg 
  • PKA:0.30±0.10(Predicted) 
  • Flash Point:84.4 °C 
  • PSA:42.85000 
  • Density:1.136 g/cm3 
  • LogP:0.67920 
  • Storage Temp.:Keep in dark place,Sealed in dry,Room Temperature 
  • Solubility.:Chloroform (Slightly), Methanol (Slightly) 
  • XLogP3:0.2
  • Hydrogen Bond Donor Count:0
  • Hydrogen Bond Acceptor Count:3
  • Rotatable Bond Count:1
  • Exact Mass:122.048012819
  • Heavy Atom Count:9
  • Complexity:114
Purity/Quality:

99%min *data from raw suppliers

Acetylpyrazine *data from reagent suppliers

Safty Information:
  • Pictogram(s): IrritantXi 
  • Hazard Codes:Xi 
  • Statements: 36/37/38 
  • Safety Statements: 26-36-24/25 
MSDS Files:

SDS file from LookChem

Useful:
  • Canonical SMILES:CC(=O)C1=NC=CN=C1
  • Description 2-acetylpyrazine is white to pale yellow crystalline powder with a nutty, popcorn, bread-crust odor. It is soluble in water and stable under ordinary conditions. It is used to manufacture many polycyclic compounds and used as useful structures in pharmaceuticals and perfumes. It is a component of the folates (vitamin B compounds) and of the isoalloxazine ring nucleus of flavins. Numerous pyrazine derivatives such as pyrazine polycyclic compounds, alkyl-, alicyclic-, and alkylaryl-substituted compounds, derivatives containing oxygenated functional groups and thio-functional groups in the side-chains are used in biological, drug, flavoring and perfumery industry. 2-acetylpyrazine is used as food additive, commonly used in chocolate and baked goods.
  • Uses Acetylpyrazine has been used in synthesis of:7-heteroaryl-pyrazolo[1,5-a]pyrimidine-3-carboxamidescopper (II) complexes with di-imine ligandsN(4) substituted thiosemicarbazones
Technology Process of Acetylpyrazine

There total 22 articles about Acetylpyrazine which guide to synthetic route it. The literature collected by LookChem mainly comes from the sharing of users and the free literature resources found by Internet computing technology. We keep the original model of the professional version of literature to make it easier and faster for users to retrieve and use. At the same time, we analyze and calculate the most feasible synthesis route with the highest yield for your reference as below:

synthetic route:
Guidance literature:
With NH4S2O8; silver nitrate; trifluoroacetic acid; In dichloromethane; water; at 40 ℃; for 2.5h;
DOI:10.1021/jo00008a050
Guidance literature:
With Eosin Y; di-tert-butyl 1,4-dihydro-2,6-dimethyl-3,5-pyridine-dicarboxylate; In acetonitrile; at 20 ℃; for 3h; chemoselective reaction; Inert atmosphere; Irradiation;
DOI:10.1039/d1ob00260k
Guidance literature:
methylene chloride; With iodine; magnesium; In tetrahydrofuran; at 60 ℃; for 2h; Inert atmosphere;
2-pyrazine carbonitrile; With copper(l) chloride; In tetrahydrofuran; at 50 ℃; for 14h; Inert atmosphere;
With water; In tetrahydrofuran; Temperature; Reagent/catalyst; Solvent; Inert atmosphere;
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