dibenzo[a,j]acridin-6-ol

Base Information

• Chemical Name: dibenzo[a,j]acridin-6-ol
• CAS No.: 67977-03-1
• Molecular Formula: C21H13NO
• Molecular Weight: 295.334
• Mol file: 67977-03-1.mol

Synonyms:

Chemical Property of dibenzo[a,j]acridin-6-ol

Chemical Property:

• Vapor Pressure: 1.23E-14mmHg at 25°C
• Boiling Point: 592.6°Cat760mmHg
• Flash Point: 312.2°C
• Density: 1.357g/cm³

Purity/Quality:

Safty Information:

• Pictogram(s):  
• Hazard Codes: 

MSDS Files:

SDS file from LookChem

Useful:

Technology Process of dibenzo[a,j]acridin-6-ol

There total 8 articles about dibenzo[a,j]acridin-6-ol which guide to synthetic route it. The literature collected by LookChem mainly comes from the sharing of users and the free literature resources found by Internet computing technology. We keep the original model of the professional version of literature to make it easier and faster for users to retrieve and use. At the same time, we analyze and calculate the most feasible synthesis route with the highest yield for your reference as below:

synthetic route:

Reference yield: 78.0%

4b,5a-dihydrodibenzoxirenoacridine (67976-98-1,117066-32-7,117019-73-5) → 6-hydroxydibenzacridine (67977-03-1)

Guidance literature:

With acetic acid; In 1,4-dioxane; for 36h; Ambient temperature;

DOI:10.1021/jo00382a017

Reference yield:

1-dimethylaminomethyl-naphthalen-2-ol (5419-02-3) → 6-hydroxydibenzacridine (67977-03-1)

Guidance literature:

Multi-step reaction with 4 steps

1: 0.5 g / 0.5 h / 260 - 280 °C

2: 83 percent / 10percent Pd/C / various solvent(s) / 8 h / 190 °C

3: 9 percent / NH₄HSO₄, 5percent aq. NaClO / CH₂Cl₂ / 6 h

4: 78 percent / 25percent CH₃COOH / dioxane / 36 h / Ambient temperature

With ammonium bisulphate; sodium hypochlorite; acetic acid; palladium on activated charcoal; In 1,4-dioxane; dichloromethane;

DOI:10.1021/jo00382a017

Reference yield:

6-amino-1,2,3,4-tetrahydronaphthalene (2217-43-8) → 6-hydroxydibenzacridine (67977-03-1)

Guidance literature:

Multi-step reaction with 4 steps

1: 0.5 g / 0.5 h / 260 - 280 °C

2: 83 percent / 10percent Pd/C / various solvent(s) / 8 h / 190 °C

3: 9 percent / NH₄HSO₄, 5percent aq. NaClO / CH₂Cl₂ / 6 h

4: 78 percent / 25percent CH₃COOH / dioxane / 36 h / Ambient temperature

With ammonium bisulphate; sodium hypochlorite; acetic acid; palladium on activated charcoal; In 1,4-dioxane; dichloromethane;

DOI:10.1021/jo00382a017

upstream raw materials:

4b,5a-dihydrodibenzoxirenoacridine

1-dimethylaminomethyl-naphthalen-2-ol

dibenz[a,j]acridine

6-amino-1,2,3,4-tetrahydronaphthalene

Downstream raw materials:

trans-5,6-dihydro-5,6-dihydroxydibenzacridine

Refernces

• 1、 Kitahara,Okuda,Shudo,Okamoto,Nagao,Seino,Sugimura. "Synthesis and mutagenicity of 10-azabenzo[a]pyrene-4,5-oxide and other pentacyclic aza-arene oxides". . p. 1950 - 1953. Retrieved 2007/10/04.