4-amino-5-(2-ethoxyphenyl)-4H-1,2,4-triazole-3-thiol

Base Information

Chemical Name:4-amino-5-(2-ethoxyphenyl)-4H-1,2,4-triazole-3-thiol
CAS No.:851879-31-7
Molecular Formula:C10H12N4OS
Molecular Weight:236.29300
Hs Code.:
DSSTox Substance ID:DTXSID901167117
Nikkaji Number:J2.517.801G
Mol file:851879-31-7.mol

Synonyms:4-amino-5-(2-ethoxyphenyl)-4H-1,2,4-triazole-3-thiol;851879-31-7;4-amino-3-(2-ethoxyphenyl)-1H-1,2,4-triazole-5-thione;SCHEMBL4559681;DTXSID901167117;HMS1767H16;MFCD06655276;AKOS008987367;BP-11235;BS-29487;CS-0213023;EN300-12289;J-514378;Z85921190;4-Amino-5-(2-ethoxyphenyl)-2H-1,2,4-triazole-3(4H)-thione;4-Amino-5-(2-ethoxyphenyl)-2,4-dihydro-3H-1,2,4-triazole-3-thione

Suppliers and Price of 4-amino-5-(2-ethoxyphenyl)-4H-1,2,4-triazole-3-thiol

Supply Marketing:

Business phase:: The product has achieved commercial mass production^*data from LookChem market partment

Manufacturers and distributors:

Manufacture/Brand
Chemicals and raw materials
Packaging
price

SynQuest Laboratories
4-Amino-5-(2-ethoxyphenyl)-4H-1,2,4-triazole-3-thiol
500 mg
$ 404.00

Crysdot
4-Amino-5-(2-ethoxyphenyl)-4H-1,2,4-triazole-3-thiol 97%
1g
$ 376.00

AK Scientific
4-Amino-5-(2-ethoxyphenyl)-4H-1,2,4-triazole-3-thiol
250mg
$ 240.00

Total 3 raw suppliers

Chemical Property of 4-amino-5-(2-ethoxyphenyl)-4H-1,2,4-triazole-3-thiol

Chemical Property:

PSA：100.95000
LogP:2.30140
XLogP3:1.2
Hydrogen Bond Donor Count:2
Hydrogen Bond Acceptor Count:4
Rotatable Bond Count:3
Exact Mass:236.07318219
Heavy Atom Count:16
Complexity:307

Purity/Quality:

99% ^*data from raw suppliers

4-Amino-5-(2-ethoxyphenyl)-4H-1,2,4-triazole-3-thiol ^*data from reagent suppliers

Safty Information:

Pictogram(s):
Hazard Codes:

MSDS Files:: SDS file from LookChem

Useful:

Canonical SMILES:CCOC1=CC=CC=C1C2=NNC(=S)N2N

Technology Process of 4-amino-5-(2-ethoxyphenyl)-4H-1,2,4-triazole-3-thiol

There total 5 articles about 4-amino-5-(2-ethoxyphenyl)-4H-1,2,4-triazole-3-thiol which guide to synthetic route it. The literature collected by LookChem mainly comes from the sharing of users and the free literature resources found by Internet computing technology. We keep the original model of the professional version of literature to make it easier and faster for users to retrieve and use. At the same time, we analyze and calculate the most feasible synthesis route with the highest yield for your reference as below:

synthetic route:

Reference yield:

: 19982-41-3
N'-(2-ethoxy-benzoyl)-hydrazinecarbodithioic acid; potassium salt

: 851879-31-7
4-amino-5-(2-ethoxy-phenyl)-2,4-dihydro-[1,2,4]triazole-3-thione

Guidance literature:: With hydrazine hydrate; In water; at 113 ℃; for 0.75h;
DOI:10.1016/j.bmcl.2008.01.028

Reference yield:

: 6290-24-0
ethyl 2-ethoxybenzoate

: 851879-31-7
4-amino-5-(2-ethoxy-phenyl)-2,4-dihydro-[1,2,4]triazole-3-thione

Guidance literature:: Multi-step reaction with 3 steps

1: hydrazine hydrate / Microwave irradiation; Reflux

2: potassium hydroxide / ethanol

3: hydrazine hydrate / Microwave irradiation

With hydrazine hydrate; potassium hydroxide; In ethanol;
DOI:10.3184/174751912X13364636691591

Reference yield:

: 21018-13-3
2-ethoxybenzoic acid hydrazide

: 851879-31-7
4-amino-5-(2-ethoxy-phenyl)-2,4-dihydro-[1,2,4]triazole-3-thione

Guidance literature:: Multi-step reaction with 2 steps

1: potassium hydroxide / ethanol

2: hydrazine hydrate / Microwave irradiation

With hydrazine hydrate; potassium hydroxide; In ethanol;
DOI:10.3184/174751912X13364636691591