(4R)-4-(Phenylsulfanyl)azetidin-2-one

Base Information

Chemical Name:(4R)-4-(Phenylsulfanyl)azetidin-2-one
CAS No.:85270-00-4
Molecular Formula:C9H9NOS
Molecular Weight:179.243
Hs Code.:
DSSTox Substance ID:DTXSID80536670
Wikidata:Q82411403

Synonyms:85270-00-4;(4R)-4-(Phenylsulfanyl)azetidin-2-one;SCHEMBL11036165;DTXSID80536670

Suppliers and Price of (4R)-4-(Phenylsulfanyl)azetidin-2-one

Supply Marketing:

Business phase:: The product has achieved commercial mass production^*data from LookChem market partment

Manufacturers and distributors:

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Chemical Property of (4R)-4-(Phenylsulfanyl)azetidin-2-one

Chemical Property:

XLogP3:1.6
Hydrogen Bond Donor Count:1
Hydrogen Bond Acceptor Count:2
Rotatable Bond Count:2
Exact Mass:179.04048508
Heavy Atom Count:12
Complexity:177

Purity/Quality:

Safty Information:

Pictogram(s):
Hazard Codes:

MSDS Files:: SDS file from LookChem

Useful:

Canonical SMILES:C1C(NC1=O)SC2=CC=CC=C2
Isomeric SMILES:C1[C@H](NC1=O)SC2=CC=CC=C2

Technology Process of (4R)-4-(Phenylsulfanyl)azetidin-2-one

There total 5 articles about (4R)-4-(Phenylsulfanyl)azetidin-2-one which guide to synthetic route it. The literature collected by LookChem mainly comes from the sharing of users and the free literature resources found by Internet computing technology. We keep the original model of the professional version of literature to make it easier and faster for users to retrieve and use. At the same time, we analyze and calculate the most feasible synthesis route with the highest yield for your reference as below:

synthetic route:

Reference yield: 48.6%

: 930-69-8
sodium thiophenolate

: 100188-48-5
3-(trimethylsilyl)-2-oxoazetidin-4-yl acetate

: 85270-00-4
(4R)-4-phenylthio-2-azetidinone

: 100188-51-0
(3S,4R)-3-(trimethylsilyl)-4-(phenylthio)-2-azetidinone

Guidance literature:: In methanol; at 25 ℃; for 3h;
DOI:10.1021/jo00354a034

Reference yield: 28.0%

: 90497-61-3,99746-85-7,31899-01-1
4-(phenylsulfonyl)-2-azetidinone

: 108-98-5
thiophenol

: 85270-00-4
(4R)-4-phenylthio-2-azetidinone

Guidance literature:: With Cinchonidin; In benzene; at 35 ℃; for 62.5h;
DOI:10.1039/c39820001324

Reference yield:

: (+)-3-phenylsulphinylpropionamide

: 85270-00-4
(4R)-4-phenylthio-2-azetidinone

: 90497-62-4
(4S)-4-phenylthio-2-azetidinone

Guidance literature:: With trimethylsilyl trifluoromethanesulfonate; N-ethyl-N,N-diisopropylamine; In dichloromethane; at 0 ℃; Yield given. Yields of byproduct given. Title compound not separated from byproducts;
DOI:10.1039/c39870001511