5-Methoxy-2-phenyl-4-pyrimidinol

Base Information

• Chemical Name: 5-Methoxy-2-phenyl-4-pyrimidinol
• CAS No.: 85386-21-6
• Molecular Formula: C11H10N2O2
• Molecular Weight: 202.213
• DSSTox Substance ID: DTXSID901285767
• ChEMBL ID: CHEMBL1539449

Synonyms:5-Methoxy-2-phenyl-4-pyrimidinol;85386-21-6;5-methoxy-2-phenylpyrimidin-4-ol;5-methoxy-2-phenyl-1H-pyrimidin-6-one;Bionet2_000264;MLS000755849;SCHEMBL9696100;CHEMBL1539449;DTXSID901285767;HMS1364L22;HMS2599C11;MFCD00215410;5-Methoxy-2-phenyl-4-pyrimidinol #;AKOS005082533;AKOS026715763;1J-310S;5-Methoxy-2-phenyl-4(3H)-pyrimidinone;5-methoxy-2-phenylpyrimidin-4(3H)-one;SMR000337872;Pyrimidine, 2-phenyl-4-hydroxy-5-methoxy-;AC-907/30063038;F2147-2320

Chemical Property of 5-Methoxy-2-phenyl-4-pyrimidinol

Chemical Property:

• XLogP3: 1.1
• Hydrogen Bond Donor Count: 1
• Hydrogen Bond Acceptor Count: 3
• Rotatable Bond Count: 2
• Exact Mass: 202.074227566
• Heavy Atom Count: 15
• Complexity: 315

Purity/Quality:

Safty Information:

• Pictogram(s):  
• Hazard Codes: 

MSDS Files:

Useful:

• Canonical SMILES: COC1=CN=C(NC1=O)C2=CC=CC=C2

Technology Process of 5-Methoxy-2-phenyl-4-pyrimidinol

There total 2 articles about 5-Methoxy-2-phenyl-4-pyrimidinol which guide to synthetic route it. The literature collected by LookChem mainly comes from the sharing of users and the free literature resources found by Internet computing technology. We keep the original model of the professional version of literature to make it easier and faster for users to retrieve and use. At the same time, we analyze and calculate the most feasible synthesis route with the highest yield for your reference as below:

synthetic route:

Reference yield:

methyl methoxyacetate (6290-49-9) + benzamidine monohydrochloride (1670-14-0) + formic acid ethyl ester (109-94-4) → 2-phenyl-4-hydroxy-5-methoxypyrimidine (85386-21-6)

Guidance literature:

With sodium; Yield given. Multistep reaction; 1.) toluene, ca.20 deg C, 2.) ethanol, reflux, 5 h;

DOI:10.1007/BF00957929

Reference yield:

→ 2-phenyl-4-hydroxy-5-methoxypyrimidine (85386-21-6)

Guidance literature:

Benzamidin-hydrochlorid, EtOH, Natrium-β-hydroxy-α-methoxy-acrylsaeure-methylester, NaOC2H5, sd.EtOH;

Reference yield: 82.0%

2-phenyl-4-hydroxy-5-methoxypyrimidine (85386-21-6) → 2-phenyl-4-chloro-5-methoxypyrimidine (13317-67-4)

Guidance literature:

With thionyl chloride; In N,N-dimethyl-formamide; for 2h; Heating;

DOI:10.1007/BF00957929

upstream raw materials:

methyl methoxyacetate

benzamidine monohydrochloride

formic acid ethyl ester

Downstream raw materials:

2-phenyl-4-chloro-5-methoxypyrimidine

2-phenyl-5-methoxypyrimidine

Post a RFQ

Cas No.:

Product Name:

Quantity:

Please select Metric Ton KG G Pound L ML

Email:

Company name:

Valid Period:

Detailed Requirements:

• Sample
• MOQ
• GMP
• FDA
• Price
  FOB CIF CFR EXW
• Urgent purchase

Enter 15 to 2000 letters.Word count: 0 letters

Attach files(File Format: Jpeg, Jpg, Gif, Png, PDF, PPT, Zip, Rar,Word or Excel Maximum File Size: 3MB)

Remove

Submit

1

What can I do for you?
Get Best Price

Get Best Price for 85386-21-6 4(1H)-Pyrimidinone, 5-methoxy-2-phenyl-

Send

Send

Metric Ton KG G Pound L ML

Send

Send