4-Cyclopentyl-N-ethylaniline

Base Information

• Chemical Name: 4-Cyclopentyl-N-ethylaniline
• CAS No.: 85603-06-1
• Molecular Formula: C13H19N
• Molecular Weight: 189.29700
• DSSTox Substance ID: DTXSID70574763
• Wikidata: Q82463921
• Mol file: 85603-06-1.mol

Synonyms:4-Cyclopentyl-N-ethylaniline;85603-06-1;DTXSID70574763

Chemical Property of 4-Cyclopentyl-N-ethylaniline

Chemical Property:

• PSA: 12.03000
• LogP: 3.84900
• XLogP3: 4.4
• Hydrogen Bond Donor Count: 1
• Hydrogen Bond Acceptor Count: 1
• Rotatable Bond Count: 3
• Exact Mass: 189.151749610
• Heavy Atom Count: 14
• Complexity: 153

Purity/Quality:

Safty Information:

• Pictogram(s):  
• Hazard Codes: 

MSDS Files:

SDS file from LookChem

Useful:

• Canonical SMILES: CCNC1=CC=C(C=C1)C2CCCC2

Technology Process of 4-Cyclopentyl-N-ethylaniline

There total 1 articles about 4-Cyclopentyl-N-ethylaniline which guide to synthetic route it. The literature collected by LookChem mainly comes from the sharing of users and the free literature resources found by Internet computing technology. We keep the original model of the professional version of literature to make it easier and faster for users to retrieve and use. At the same time, we analyze and calculate the most feasible synthesis route with the highest yield for your reference as below:

synthetic route:

Reference yield: 97.0%

N-(4-Cyclopentylphenyl)acetamide (85602-98-8) → N-Ethyl-4-cyclopentylaniline (85603-06-1)

Guidance literature:

With lithium aluminium tetrahydride; In diethyl ether; benzene; for 5h; Heating;

DOI:10.1135/cccc19830156

Reference yield: 100.0%

N-Ethyl-4-cyclopentylaniline (85603-06-1) + chloroacetyl chloride (79-04-9) → N-(4-cyclopentylphenyl)-N-ethylchloroacetamide (85603-18-5)

Guidance literature:

With potassium carbonate; In chloroform; for 1.5h; Heating;

DOI:10.1135/cccc19830156

Reference yield:

N-Ethyl-4-cyclopentylaniline (85603-06-1) → N-(4-Cyclopentyl-phenyl)-N-ethyl-2-piperidin-1-yl-acetamide (85603-19-6)

Guidance literature:

Multi-step reaction with 2 steps

1: 100 percent / K₂CO₃ / CHCl₃ / 1.5 h / Heating

2: 83 percent / benzene / 6 h / Heating

With potassium carbonate; In chloroform; benzene;

DOI:10.1135/cccc19830156

upstream raw materials:

N-(4-Cyclopentylphenyl)acetamide

Downstream raw materials:

N-(4-cyclopentylphenyl)-N-ethylchloroacetamide

(4-Cyclopentyl-phenyl)-ethyl-(2-piperidin-1-yl-ethyl)-amine

N-(4-Cyclopentyl-phenyl)-N-ethyl-2-piperidin-1-yl-acetamide