1-(Benzenesulfonyl)-2-[(morpholin-4-yl)methyl]-3-(phenylsulfanyl)-1H-indole

Base Information

Chemical Name:1-(Benzenesulfonyl)-2-[(morpholin-4-yl)methyl]-3-(phenylsulfanyl)-1H-indole
CAS No.:85678-46-2
Molecular Formula:C25H24N2O3S2
Molecular Weight:464.609
Hs Code.:
DSSTox Substance ID:DTXSID90510840
Wikidata:Q82369366

Synonyms:85678-46-2;DTXSID90510840;1-(Benzenesulfonyl)-2-[(morpholin-4-yl)methyl]-3-(phenylsulfanyl)-1H-indole

Suppliers and Price of 1-(Benzenesulfonyl)-2-[(morpholin-4-yl)methyl]-3-(phenylsulfanyl)-1H-indole

Supply Marketing:

Business phase:: The product has achieved commercial mass production^*data from LookChem market partment

Manufacturers and distributors:

Manufacture/Brand
Chemicals and raw materials
Packaging
price

Total 0 raw suppliers

Chemical Property of 1-(Benzenesulfonyl)-2-[(morpholin-4-yl)methyl]-3-(phenylsulfanyl)-1H-indole

Chemical Property:

XLogP3:4.8
Hydrogen Bond Donor Count:0
Hydrogen Bond Acceptor Count:5
Rotatable Bond Count:6
Exact Mass:464.12283498
Heavy Atom Count:32
Complexity:695

Purity/Quality:

Safty Information:

Pictogram(s):
Hazard Codes:

MSDS Files:: SDS file from LookChem

Useful:

Canonical SMILES:C1COCCN1CC2=C(C3=CC=CC=C3N2S(=O)(=O)C4=CC=CC=C4)SC5=CC=CC=C5

Technology Process of 1-(Benzenesulfonyl)-2-[(morpholin-4-yl)methyl]-3-(phenylsulfanyl)-1H-indole

There total 4 articles about 1-(Benzenesulfonyl)-2-[(morpholin-4-yl)methyl]-3-(phenylsulfanyl)-1H-indole which guide to synthetic route it. The literature collected by LookChem mainly comes from the sharing of users and the free literature resources found by Internet computing technology. We keep the original model of the professional version of literature to make it easier and faster for users to retrieve and use. At the same time, we analyze and calculate the most feasible synthesis route with the highest yield for your reference as below:

synthetic route:

Reference yield: 94.0%

: 110-91-8,99108-56-2
morpholine

: 85678-42-8
2-(bromomethyl)-3-(phenylthio)-1-(phenylsulfonyl)-1H-indole

: 85678-46-2
1-Benzenesulfonyl-2-morpholin-4-ylmethyl-3-phenylsulfanyl-1H-indole

Guidance literature:: In tetrachloromethane; Ambient temperature;
DOI:10.1055/s-1983-30265

Reference yield:

: 56366-45-1
2-methyl-3-phenylthioindole

: 85678-46-2
1-Benzenesulfonyl-2-morpholin-4-ylmethyl-3-phenylsulfanyl-1H-indole

Guidance literature:: Multi-step reaction with 3 steps

1: 83 percent / NaH / dimethylsulfoxide

2: 98 percent / N-bromosuccinimide, benzoyl peroxide / CCl₄ / 5 h / Heating

3: 94 percent / CCl₄ / Ambient temperature

With N-Bromosuccinimide; Perbenzoic acid; sodium hydride; In tetrachloromethane; dimethyl sulfoxide;
DOI:10.1055/s-1983-30265

Reference yield:

: 85678-41-7
N-benzenesulphonyl-2-methyl-3-thiophenoxyindole

: 85678-46-2
1-Benzenesulfonyl-2-morpholin-4-ylmethyl-3-phenylsulfanyl-1H-indole

Guidance literature:: Multi-step reaction with 2 steps

1: 98 percent / N-bromosuccinimide, benzoyl peroxide / CCl₄ / 5 h / Heating

2: 94 percent / CCl₄ / Ambient temperature

With N-Bromosuccinimide; Perbenzoic acid; In tetrachloromethane;
DOI:10.1055/s-1983-30265