L-Leucinamide, 1-(((2-chloroethyl)nitrosoamino)carbonyl)-L-prolyl-

Base Information

Chemical Name:L-Leucinamide, 1-(((2-chloroethyl)nitrosoamino)carbonyl)-L-prolyl-
CAS No.:83472-40-6
Molecular Formula:C₁₄H₂₄ClN₅O₄
Molecular Weight:361.829
Hs Code.:
DSSTox Substance ID:DTXSID20232361
Wikidata:Q76156834
Mol file:83472-40-6.mol

Synonyms:83472-40-6;L-Leucinamide, 1-(((2-chloroethyl)nitrosoamino)carbonyl)-L-prolyl-;BRN 5637862;(2S)-2-N-[(2S)-1-amino-4-methyl-1-oxopentan-2-yl]-1-N-(2-chloroethyl)-1-N-nitrosopyrrolidine-1,2-dicarboxamide;1-(((2-Chloroethyl)nitrosoamino)carbonyl)-L-prolyl-L-leucinamide;N-(Chloro-2 ethyl) N-nitrosocarbamoyl L-prolyl L-leucinamide [French];N-(Chloro-2 ethyl) N-nitrosocarbamoyl L-prolyl L-leucinamide;DTXSID20232361;LS-87792

Suppliers and Price of L-Leucinamide, 1-(((2-chloroethyl)nitrosoamino)carbonyl)-L-prolyl-

Supply Marketing:

Business phase:: The product has achieved commercial mass production^*data from LookChem market partment

Manufacturers and distributors:

Manufacture/Brand
Chemicals and raw materials
Packaging
price

American Custom Chemicals Corporation
1-(((2-CHLOROETHYL)NITROSOAMINO)CARBONYL)-L-PROLYL-L-LEUCINAMIDE 95.00%
5MG
$ 495.21

Total 3 raw suppliers

Chemical Property of L-Leucinamide, 1-(((2-chloroethyl)nitrosoamino)carbonyl)-L-prolyl-

Chemical Property:

PSA：129.65000
Density:1.42g/cm³
LogP:2.73710
XLogP3:0.6
Hydrogen Bond Donor Count:2
Hydrogen Bond Acceptor Count:5
Rotatable Bond Count:7
Exact Mass:361.1516820
Heavy Atom Count:24
Complexity:488

Purity/Quality:: 1-(((2-CHLOROETHYL)NITROSOAMINO)CARBONYL)-L-PROLYL-L-LEUCINAMIDE 95.00% ^*data from reagent suppliers

Safty Information:

Pictogram(s):
Hazard Codes:

MSDS Files:: SDS file from LookChem

Useful:

Canonical SMILES:CC(C)CC(C(=O)N)NC(=O)C1CCCN1C(=O)N(CCCl)N=O
Isomeric SMILES:CC(C)C[C@@H](C(=O)N)NC(=O)[C@@H]1CCCN1C(=O)N(CCCl)N=O

Technology Process of L-Leucinamide, 1-(((2-chloroethyl)nitrosoamino)carbonyl)-L-prolyl-

There total 2 articles about L-Leucinamide, 1-(((2-chloroethyl)nitrosoamino)carbonyl)-L-prolyl- which guide to synthetic route it. The literature collected by LookChem mainly comes from the sharing of users and the free literature resources found by Internet computing technology. We keep the original model of the professional version of literature to make it easier and faster for users to retrieve and use. At the same time, we analyze and calculate the most feasible synthesis route with the highest yield for your reference as below:

synthetic route:

Reference yield: 78.0%

: 80354-51-4
N-(chloro-2 ethyl)N-nitrosocarbamate de trichloro-2,4,5 phenyle

: (2S)-N-[(2S)-1-amino-4-methyl-1-oxopentan-2-yl]pyrrolidine-2-carboxamide hydrochloride

: 83472-40-6
N-(chloro-2 ethyl) N-nitrosocarbamoyl L-prolyl L-leucinamide

Guidance literature:: With N-ethyl-N,N-diisopropylamine; In N,N-dimethyl-formamide; for 2h; Ambient temperature;

Reference yield:

: 29019-64-5
Z-L-Pro-L-Leu-NH₂

: 83472-40-6
N-(chloro-2 ethyl) N-nitrosocarbamoyl L-prolyl L-leucinamide

Guidance literature:: Multi-step reaction with 2 steps

1: H₂, cc.HCl / Pd/C / ethanol / 5 h

2: 78 percent / N,N-diisopropyl N-ethylamine / dimethylformamide / 2 h / Ambient temperature

With hydrogenchloride; hydrogen; N-ethyl-N,N-diisopropylamine; palladium on activated charcoal; In ethanol; N,N-dimethyl-formamide;