(2S)-3-Amino-2-(benzyloxy)propan-1-OL

Base Information

Chemical Name:(2S)-3-Amino-2-(benzyloxy)propan-1-OL
CAS No.:85820-86-6
Molecular Formula:C10H15NO2
Molecular Weight:181.235
Hs Code.:
DSSTox Substance ID:DTXSID90528081
Wikidata:Q82397435

Synonyms:85820-86-6;(2S)-3-AMINO-2-(BENZYLOXY)PROPAN-1-OL;DTXSID90528081

Suppliers and Price of (2S)-3-Amino-2-(benzyloxy)propan-1-OL

Supply Marketing:

Business phase:: The product has achieved commercial mass production^*data from LookChem market partment

Manufacturers and distributors:

Manufacture/Brand
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Total 0 raw suppliers

Chemical Property of (2S)-3-Amino-2-(benzyloxy)propan-1-OL

Chemical Property:

XLogP3:0
Hydrogen Bond Donor Count:2
Hydrogen Bond Acceptor Count:3
Rotatable Bond Count:5
Exact Mass:181.110278721
Heavy Atom Count:13
Complexity:124

Purity/Quality:

Safty Information:

Pictogram(s):
Hazard Codes:

MSDS Files:: SDS file from LookChem

Useful:

Canonical SMILES:C1=CC=C(C=C1)COC(CN)CO
Isomeric SMILES:C1=CC=C(C=C1)CO[C@@H](CN)CO

Technology Process of (2S)-3-Amino-2-(benzyloxy)propan-1-OL

There total 2 articles about (2S)-3-Amino-2-(benzyloxy)propan-1-OL which guide to synthetic route it. The literature collected by LookChem mainly comes from the sharing of users and the free literature resources found by Internet computing technology. We keep the original model of the professional version of literature to make it easier and faster for users to retrieve and use. At the same time, we analyze and calculate the most feasible synthesis route with the highest yield for your reference as below:

synthetic route:

Reference yield: 76.0%

: 1397262-04-2
N-[(2S)-2-benzyloxy-3-(trityloxy)propyl]-N-tritylamine

: 85820-86-6
(2S)-3-amino-2-(benzyloxy)propan-1-ol

Guidance literature:: With trifluoroacetic acid; In dichloromethane; at 20 ℃; for 24h;
DOI:10.1021/jm3008008

Reference yield:

: 100-39-0
benzyl bromide

: 85820-86-6
(2S)-3-amino-2-(benzyloxy)propan-1-ol

Guidance literature:: Multi-step reaction with 2 steps

1.1: sodium hydride / dimethyl sulfoxide / 0.5 h / 20 °C

1.2: 17 h / 20 °C

2.1: trifluoroacetic acid / dichloromethane / 24 h / 20 °C

With sodium hydride; trifluoroacetic acid; In dichloromethane; dimethyl sulfoxide;
DOI:10.1021/jm3008008