1-Naphthalenecarboxylic acid, 8-iodo-, methyl ester

Base Information

Chemical Name:1-Naphthalenecarboxylic acid, 8-iodo-, methyl ester
CAS No.:85864-85-3
Molecular Formula:C12H9IO2
Molecular Weight:312.107
Hs Code.:
DSSTox Substance ID:DTXSID40385005
Wikidata:Q82177528

Synonyms:85864-85-3;methyl 8-iodonaphthalene-1-carboxylate;methyl 8-iodo-1-naphthoate;1-Naphthalenecarboxylic acid, 8-iodo-, methyl ester;Maybridge3_004293;DTXSID40385005;HMS1443D03;CCG-41475;IDI1_015680;SR-01000631547-1

Suppliers and Price of 1-Naphthalenecarboxylic acid, 8-iodo-, methyl ester

Supply Marketing:

Business phase:: The product has achieved commercial mass production^*data from LookChem market partment

Manufacturers and distributors:

Manufacture/Brand
Chemicals and raw materials
Packaging
price

Alichem
Methyl8-iodonaphthalene-1-carboxylate
1g
$ 1802.95

Alichem
Methyl8-iodonaphthalene-1-carboxylate
500mg
$ 970.20

Alichem
Methyl8-iodonaphthalene-1-carboxylate
250mg
$ 714.00

Total 3 raw suppliers

Chemical Property of 1-Naphthalenecarboxylic acid, 8-iodo-, methyl ester

Chemical Property:

PSA：26.30000
LogP:3.23100
XLogP3:3.7
Hydrogen Bond Donor Count:0
Hydrogen Bond Acceptor Count:2
Rotatable Bond Count:2
Exact Mass:311.96473
Heavy Atom Count:15
Complexity:242

Purity/Quality:: Methyl8-iodonaphthalene-1-carboxylate ^*data from reagent suppliers

Safty Information:

Pictogram(s):
Hazard Codes:

MSDS Files:: SDS file from LookChem

Useful:

Canonical SMILES:COC(=O)C1=CC=CC2=C1C(=CC=C2)I

Technology Process of 1-Naphthalenecarboxylic acid, 8-iodo-, methyl ester

There total 5 articles about 1-Naphthalenecarboxylic acid, 8-iodo-, methyl ester which guide to synthetic route it. The literature collected by LookChem mainly comes from the sharing of users and the free literature resources found by Internet computing technology. We keep the original model of the professional version of literature to make it easier and faster for users to retrieve and use. At the same time, we analyze and calculate the most feasible synthesis route with the highest yield for your reference as below:

synthetic route:

Reference yield: 98.0%

: 186581-53-3,908094-01-9,334-88-3
diazomethane

: 13577-19-0
8-iodo-1-naphthoic acid

: 85864-85-3
methyl 8-iodo-1-naphthoate

Guidance literature:: In diethyl ether; at 0 ℃; for 1h;
DOI:10.1135/cccc20030907

Reference yield:

: 518-05-8
Naphthalene-1,8-dicarboxylic acid

: 85864-85-3
methyl 8-iodo-1-naphthoate

Guidance literature:: Multi-step reaction with 2 steps

2: methanol; diethyl ether / 0 °C

In methanol; diethyl ether;
DOI:10.1021/ja00357a021

Reference yield:

: 130-00-7
1,8-naphtholactam

: 85864-85-3
methyl 8-iodo-1-naphthoate

Guidance literature:: Multi-step reaction with 3 steps

1.1: aq. NaOH / methanol / 20 h / Heating

2.1: aq. HCl; NaNO₂ / methanol / 0.25 h / -5 °C

2.2: 10.8 g / aq. NaI; urea / methanol / 5 h / 0 - 50 °C

3.1: 98 percent / diethyl ether / 1 h / 0 °C

With hydrogenchloride; sodium hydroxide; sodium nitrite; In methanol; diethyl ether; 2.2: Sandmeyer reaction;
DOI:10.1135/cccc20030907