6-Chloro-2-piperazino-4-dimethylamino-7-benzylamino-pteridine

Base Information

Chemical Name:6-Chloro-2-piperazino-4-dimethylamino-7-benzylamino-pteridine
CAS No.:96801-85-3
Molecular Formula:C₁₉H₂₃ClN₈
Molecular Weight:398.898
Hs Code.:
DSSTox Substance ID:DTXSID90242518
Nikkaji Number:J1.042.003B
Wikidata:Q83126261
ChEMBL ID:CHEMBL142504

Synonyms:6-Chloro-2-piperazino-4-dimethylamino-7-benzylamino-pteridine;CHEMBL142504;4,7-Pteridinediamine, 6-chloro-N(sup 4),N(sup 4)-dimethyl-N(sup 7)-(phenylmethyl)-2-(1-piperazinyl)-;96801-85-3;C19H23ClN8;SCHEMBL10705322;C19-H23-Cl-N8;DTXSID90242518;KNPLFFHAIBJZBG-UHFFFAOYSA-N;BDBM50471930;LS-126300;N,N-Dimethyl-N'-benzyl-2-(1-piperazinyl)-6-chloro-4,7-pteridinediamine

Suppliers and Price of 6-Chloro-2-piperazino-4-dimethylamino-7-benzylamino-pteridine

Supply Marketing:

Business phase:: The product has achieved commercial mass production^*data from LookChem market partment

Manufacturers and distributors:

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Chemical Property of 6-Chloro-2-piperazino-4-dimethylamino-7-benzylamino-pteridine

Chemical Property:

Vapor Pressure:2.16E-13mmHg at 25°C
Boiling Point:578.8°Cat760mmHg
Flash Point:303.8°C
Density:1.352g/cm³
XLogP3:2.9
Hydrogen Bond Donor Count:2
Hydrogen Bond Acceptor Count:8
Rotatable Bond Count:5
Exact Mass:398.1734205
Heavy Atom Count:28
Complexity:483

Purity/Quality:

Safty Information:

Pictogram(s):
Hazard Codes:

MSDS Files:: SDS file from LookChem

Useful:

Canonical SMILES:CN(C)C1=NC(=NC2=C1N=C(C(=N2)NCC3=CC=CC=C3)Cl)N4CCNCC4

Technology Process of 6-Chloro-2-piperazino-4-dimethylamino-7-benzylamino-pteridine

There total 3 articles about 6-Chloro-2-piperazino-4-dimethylamino-7-benzylamino-pteridine which guide to synthetic route it. The literature collected by LookChem mainly comes from the sharing of users and the free literature resources found by Internet computing technology. We keep the original model of the professional version of literature to make it easier and faster for users to retrieve and use. At the same time, we analyze and calculate the most feasible synthesis route with the highest yield for your reference as below:

synthetic route:

Reference yield: 50.7%

: 110-85-0
piperazine

: 96801-89-7
2,6-dichloro-4-dimethylamino-7-benzylamino-pteridine

: 96801-85-3
6-chloro-2-piperazino-4-dimethylamino-7-benzylamino-pteridine

Guidance literature:: In 1,4-dioxane; for 1h; Heating;
DOI:10.1021/jm981021v

Reference yield:

: 21071-37-4
2,4,6,7-tetrachloropteridine

: 96801-85-3
6-chloro-2-piperazino-4-dimethylamino-7-benzylamino-pteridine

Guidance literature:: Multi-step reaction with 3 steps

1: tetrahydrofuran; diethyl ether / 1 h / 0 °C

2: 94.7 percent / Et₃N / dioxane / 1 h / Ambient temperature

3: 50.7 percent / dioxane / 1 h / Heating

With triethylamine; In tetrahydrofuran; 1,4-dioxane; diethyl ether;
DOI:10.1021/jm981021v

Reference yield:

: 219128-05-9
4-dimethylamino-2,6,7-trichloropteridine

: 96801-85-3
6-chloro-2-piperazino-4-dimethylamino-7-benzylamino-pteridine

Guidance literature:: Multi-step reaction with 2 steps

1: 94.7 percent / Et₃N / dioxane / 1 h / Ambient temperature

2: 50.7 percent / dioxane / 1 h / Heating

With triethylamine; In 1,4-dioxane;
DOI:10.1021/jm981021v