Ethyl 4-(fluoromethyl)benzoate

Base Information

Chemical Name:Ethyl 4-(fluoromethyl)benzoate
CAS No.:86239-04-5
Molecular Formula:C10H11FO2
Molecular Weight:182.195
Hs Code.:
DSSTox Substance ID:DTXSID10542062
Wikidata:Q82418581

Synonyms:Ethyl 4-(fluoromethyl)benzoate;86239-04-5;SCHEMBL10948186;DTXSID10542062

Suppliers and Price of Ethyl 4-(fluoromethyl)benzoate

Supply Marketing:

Business phase:: The product has achieved commercial mass production^*data from LookChem market partment

Manufacturers and distributors:

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Total 0 raw suppliers

Chemical Property of Ethyl 4-(fluoromethyl)benzoate

Chemical Property:

XLogP3:2.8
Hydrogen Bond Donor Count:0
Hydrogen Bond Acceptor Count:3
Rotatable Bond Count:4
Exact Mass:182.07430775
Heavy Atom Count:13
Complexity:162

Purity/Quality:

Safty Information:

Pictogram(s):
Hazard Codes:

MSDS Files:: SDS file from LookChem

Useful:

Canonical SMILES:CCOC(=O)C1=CC=C(C=C1)CF

Technology Process of Ethyl 4-(fluoromethyl)benzoate

There total 4 articles about Ethyl 4-(fluoromethyl)benzoate which guide to synthetic route it. The literature collected by LookChem mainly comes from the sharing of users and the free literature resources found by Internet computing technology. We keep the original model of the professional version of literature to make it easier and faster for users to retrieve and use. At the same time, we analyze and calculate the most feasible synthesis route with the highest yield for your reference as below:

synthetic route:

Reference yield: 87.0%

: 26496-94-6
Ethyl 4-(bromomethyl)benzoate

: 86239-04-5
ethyl 4-(fluoromethyl)benzoate

Guidance literature:: With potassium fluoride; 18-crown-6 ether; In acetonitrile; for 92h; Heating;
DOI:10.1021/jm00363a013

Reference yield: 78.0%

: 373-52-4
bromofluoromethane

: 4334-88-7
p-ethoxycarbonylphenylboronic acid

: 86239-04-5
ethyl 4-(fluoromethyl)benzoate

Guidance literature:: With dmap; 1,10-Phenanthroline; (1,2-dimethoxyethane)dichloronickel(II); potassium carbonate; In 1,4-dioxane; 1,2-dimethoxyethane; at 70 ℃; for 24h; Schlenk technique; Inert atmosphere;
DOI:10.1002/anie.201502882

Reference yield: 45.0%

: 51934-41-9
4-iodobenzoic acid ethyl ester

: sodium monofluoromethanesulfinate

: 86239-04-5
ethyl 4-(fluoromethyl)benzoate

Guidance literature:: With dmap; (1,2-dimethoxyethane)dichloronickel(II); tetrabutylammonium tetrafluoroborate; potassium carbonate; 4,4'-di-tert-butyl-2,2'-bipyridine; In dimethyl sulfoxide; at 30 ℃; for 8h; Sealed tube; Inert atmosphere; Electrolysis;
DOI:10.1021/acs.orglett.1c02997