N-(2,3-Dimethyl-1-phenyl-3-pyrazolin-5-ylidene)salicylamide

Base Information

• Chemical Name: N-(2,3-Dimethyl-1-phenyl-3-pyrazolin-5-ylidene)salicylamide
• CAS No.: 79442-83-4
• Molecular Formula: C18H17N3O2
• Molecular Weight: 307.352
• DSSTox Substance ID: DTXSID501033023
• Mol file: 79442-83-4.mol

Synonyms:BRN 4533402;N-(2,3-Dimethyl-1-phenyl-3-pyrazolin-5-ylidene)salicylamide;Salicylamide, N-(2,3-dimethyl-1-phenyl-3-pyrazolin-5-ylidene)-;Benzamide, N-(1,2-dihydro-1,5-dimethyl-2-phenyl-3H-pyrazol-3-ylidene)-2-hydroxy-;79442-83-4;DTXSID501033023;LS-144158

Chemical Property of N-(2,3-Dimethyl-1-phenyl-3-pyrazolin-5-ylidene)salicylamide

Chemical Property:

• Vapor Pressure: 2.67E-09mmHg at 25°C
• Boiling Point: 465.8°Cat760mmHg
• Flash Point: 235.5°C
• Density: 1.2g/cm³
• XLogP3: 3.9
• Hydrogen Bond Donor Count: 1
• Hydrogen Bond Acceptor Count: 3
• Rotatable Bond Count: 2
• Exact Mass: 307.132076794
• Heavy Atom Count: 23
• Complexity: 508

Purity/Quality:

Safty Information:

• Pictogram(s):  
• Hazard Codes: 

MSDS Files:

SDS file from LookChem

Useful:

• Canonical SMILES: CC1=CC(=NC(=O)C2=CC=CC=C2O)N(N1C)C3=CC=CC=C3

Technology Process of N-(2,3-Dimethyl-1-phenyl-3-pyrazolin-5-ylidene)salicylamide

There total 3 articles about N-(2,3-Dimethyl-1-phenyl-3-pyrazolin-5-ylidene)salicylamide which guide to synthetic route it. The literature collected by LookChem mainly comes from the sharing of users and the free literature resources found by Internet computing technology. We keep the original model of the professional version of literature to make it easier and faster for users to retrieve and use. At the same time, we analyze and calculate the most feasible synthesis route with the highest yield for your reference as below:

synthetic route:

Reference yield: 62.0%

N-(1-fenil-3-metilpirazol-5-il)-salicilammide (70803-10-0) + methyl salicylate (119-36-8,8024-54-2) → 2-Methoxy-N-(5-methyl-2-phenyl-2H-pyrazol-3-yl)-benzamide (79442-80-1) + N-[1,5-Dimethyl-2-phenyl-1,2-dihydro-pyrazol-(3E)-ylidene]-2-hydroxy-benzamide (79442-83-4)

Guidance literature:

for 1.5h; Product distribution; Heating;

Reference yield: 10.0%

1-Phenyl-3-methyl-5-aminopyrazole (1131-18-6) + methyl salicylate (119-36-8,8024-54-2) → 3-Methyl-5-methylamino-1-phenyl-1H-pyrazole (57047-10-6) + 2-Methoxy-N-(5-methyl-2-phenyl-2H-pyrazol-3-yl)-benzamide (79442-80-1) + N-[1,5-Dimethyl-2-phenyl-1,2-dihydro-pyrazol-(3E)-ylidene]-2-hydroxy-benzamide (79442-83-4)

Guidance literature:

for 1.5h; Product distribution; Heating;

Reference yield: 10.0%

1-phenylpyrazol-5-amine (826-85-7) + methyl salicylate (119-36-8,8024-54-2) → 3-Methyl-5-methylamino-1-phenyl-1H-pyrazole (57047-10-6) + 2-Methoxy-N-(5-methyl-2-phenyl-2H-pyrazol-3-yl)-benzamide (79442-80-1) + N-[1,5-Dimethyl-2-phenyl-1,2-dihydro-pyrazol-(3E)-ylidene]-2-hydroxy-benzamide (79442-83-4)

Guidance literature:

for 1.5h; Product distribution; Heating;

upstream raw materials:

1-phenylpyrazol-5-amine

methyl salicylate

1-Phenyl-3-methyl-5-aminopyrazole

N-(1-fenil-3-metilpirazol-5-il)-salicilammide

Downstream raw materials:

1,5-Dimethyl-2-phenyl-1,2-dihydro-pyrazol-3-ylideneamine; hydrochloride

salicylic acid