Technology Process of Benzenamine,
N,N-diphenyl-4-[5-[4-(2-pyridinyl)phenyl]-1,3,4-oxadiazol-2-yl]-
There total 2 articles about Benzenamine,
N,N-diphenyl-4-[5-[4-(2-pyridinyl)phenyl]-1,3,4-oxadiazol-2-yl]- which
guide to synthetic route it.
The literature collected by LookChem mainly comes from the sharing of users and the free literature resources found by Internet computing technology. We keep the original model of the professional version of literature to make it easier and faster for users to retrieve and use. At the same time, we analyze and calculate the most feasible synthesis route with the highest yield for your reference as below:
synthetic route:
- Guidance literature:
-
With
tetrakis(triphenylphosphine) palladium(0);
In
toluene;
at 110 ℃;
for 50h;
Inert atmosphere;
DOI:10.1016/j.dyepig.2010.08.001
- Guidance literature:
-
Multi-step reaction with 2 steps
1: pyridine / 48 h / Inert atmosphere; Reflux
2: tetrakis(triphenylphosphine) palladium(0) / toluene / 50 h / 110 °C / Inert atmosphere
With
pyridine; tetrakis(triphenylphosphine) palladium(0);
In
toluene;
2: Stille coupling;
DOI:10.1016/j.dyepig.2010.08.001
- Guidance literature:
-
With
Na2CO3;
In
2-ethoxy-ethanol; water;
(under N2, Schlenk); mixt. of ligand, K2PtCl4 stirred in 2-ethoxyethanol-H2O, heated at 80°C for 16 h, cooled to room temp., H2O added, ppt. collected, washed with H2O, vac. dried, reacted with acetylacetone and Na2CO3 at 100°C for 16 h; solvent removed under reduced pressure, residue purified with TLC on silica with CH2Cl2/ethyl acetate 10:1; elem. anal.;
DOI:10.1021/ic061566c
