7-Bromo-3-hydroxy-2-naphthoic acid

Base Information

• Chemical Name: 7-Bromo-3-hydroxy-2-naphthoic acid
• CAS No.: 1779-11-9
• Molecular Formula: C11H7BrO3
• Molecular Weight: 267.079
• Hs Code.: 29181990
• European Community (EC) Number: 678-250-0
• NSC Number: 50692
• DSSTox Substance ID: DTXSID9061960
• Nikkaji Number: J27.856D
• Wikidata: Q72456936
• ChEMBL ID: CHEMBL4247592
• Mol file: 1779-11-9.mol

Synonyms:7-bromo-3-hydroxy-2-naphthoic acid;1779-11-9;7-Bromo-3-hydroxy-naphthalene-2-carboxylic acid;7-bromo-3-hydroxynaphthalene-2-carboxylic acid;2-Naphthalenecarboxylic acid, 7-bromo-3-hydroxy-;6-bromo-2-hydroxy naphthalene-3-carboxylic acid;C11H7BrO3;7-Bromo-3-hydroxy-2-naphthalenecarboxylic acid;MFCD00137823;2-Naphthoic acid, 7-bromo-3-hydroxy-;6-Bromo-2-naphthol-3-carboxylic Acid;6-Bromo-2-hydroxynaphthalene-3-carboxylic acid;NSC50692;6-bromo-2-hydroxy-3-naphthoic acid;SCHEMBL358356;CHEMBL4247592;DTXSID9061960;7-bromo-3-hydroxy-2-naphthoicacid;BCP26749;BDBM50421645;NSC 50692;NSC-50692;AKOS005146451;AC-9214;CS-W008329;SS-3555;SY050712;AM20030180;B3180;FT-0651463;7-bromo-3-hydroxy-naphthalene-2-carboxylic acid, AldrichCPR;7-Bromo-3-hydroxy-2-naphthoic acid, >=98.0% (HPLC), 98.0-102.0 wt. % (AT)

Chemical Property of 7-Bromo-3-hydroxy-2-naphthoic acid

Chemical Property:

• Vapor Pressure: 8.17E-08mmHg at 25°C
• Melting Point: 262 °C
• Refractive Index: 1.737
• Boiling Point: 420.3 °C at 760 mmHg
• PKA: 2.81±0.30(Predicted)
• Flash Point: 208 °C
• PSA: 57.53000
• Density: 1.772 g/cm³
• LogP: 3.00610
• Storage Temp.: Sealed in dry,Room Temperature
• XLogP3: 3.6
• Hydrogen Bond Donor Count: 2
• Hydrogen Bond Acceptor Count: 3
• Rotatable Bond Count: 1
• Exact Mass: 265.95786
• Heavy Atom Count: 15
• Complexity: 256

Purity/Quality:

99% ^*data from raw suppliers

7-Bromo-3-hydroxy-2-naphthoic Acid >98.0%(GC)(T) ^*data from reagent suppliers

Safty Information:

• Pictogram(s): Xi
• Hazard Codes: Xi
• Statements: 36/37/38
• Safety Statements: 26-24/25

MSDS Files:

SDS file from LookChem

Useful:

• Canonical SMILES: C1=CC(=CC2=CC(=C(C=C21)O)C(=O)O)Br

Technology Process of 7-Bromo-3-hydroxy-2-naphthoic acid

There total 5 articles about 7-Bromo-3-hydroxy-2-naphthoic acid which guide to synthetic route it. The literature collected by LookChem mainly comes from the sharing of users and the free literature resources found by Internet computing technology. We keep the original model of the professional version of literature to make it easier and faster for users to retrieve and use. At the same time, we analyze and calculate the most feasible synthesis route with the highest yield for your reference as below:

synthetic route:

Reference yield: 96.5%

1,6-dibromo-2-hydroxynaphthalene-3-carboxylic acid (1779-10-8) → 7-bromo-3-hydroxy-2-naphthoic acid (1779-11-9)

Guidance literature:

With hydrogenchloride; tin; In acetic acid; at 125 ℃; for 12h; Reflux;

Reference yield: 75.1%

5,7-dibromo-3-hydroxy-2-naphthoic acid → 7-bromo-3-hydroxy-2-naphthoic acid (1779-11-9)

Guidance literature:

With hydrogenchloride; In water; acetic acid; for 3h; Reflux;

Reference yield:

3-Hydroxy-2-naphthoic acid (92-70-6) → 7-bromo-3-hydroxy-2-naphthoic acid (1779-11-9)

Guidance literature:

3-Hydroxy-2-naphthoic acid; With bromine; acetic acid;

With hydrogenchloride; tin; acetic acid; Heating;

DOI:10.1016/S0960-894X(02)00331-1

upstream raw materials:

1,6-dibromo-2-hydroxynaphthalene-3-carboxylic acid

3-Hydroxy-2-naphthoic acid

β-naphthol

Downstream raw materials:

7-amino-3-hydroxy-[2]naphthoic acid

7-bromo-3-hydroxy-2-naphth-o-amisidide

7-bromo-3-hydroxy-[2]naphthoic acid anilide

7-bromo-3-methoxynaphthalene-2-carboxylic acid methyl ester