9H-Imidazo(1,2-a)purin-9-one, 3,5-dihydro-3-((2-hydroxyethoxy)methyl)-5,6-dimethyl-

Base Information

Chemical Name:9H-Imidazo(1,2-a)purin-9-one, 3,5-dihydro-3-((2-hydroxyethoxy)methyl)-5,6-dimethyl-
CAS No.:114199-20-1
Molecular Formula:C₁₂H₁₅N₅O₃
Molecular Weight:277.283
Hs Code.:
ChEMBL ID:CHEMBL282200
DSSTox Substance ID:DTXSID40921301
Wikidata:Q82894107
Mol file:114199-20-1.mol

Synonyms:114199-20-1;N2-Methyl-1,N2-isopropenoacyclovir;9H-Imidazo(1,2-a)purin-9-one, 3,5-dihydro-3-((2-hydroxyethoxy)methyl)-5,6-dimethyl-;N2-Methyl-1,N2-isopropeno-9-((2-hydroxyethoxy)methyl)guanine;CHEMBL282200;DTXSID40921301;N2-Methyl-1, N2-isopropenoacyclovir;N2-Methyl-1, N2-isopropeno-9-[(2-hydroxyethoxy)methyl]guanine;3-(2-hydroxyethoxymethyl)-5,6-dimethyl-imidazo[1,2-a]purin-9-one;3-[(2-Hydroxyethoxy)methyl]-5,6-dimethyl-3,5-dihydro-9H-imidazo[1,2-a]purin-9-one

Suppliers and Price of 9H-Imidazo(1,2-a)purin-9-one, 3,5-dihydro-3-((2-hydroxyethoxy)methyl)-5,6-dimethyl-

Supply Marketing:

Business phase:: The product has achieved commercial mass production^*data from LookChem market partment

Manufacturers and distributors:

Manufacture/Brand
Chemicals and raw materials
Packaging
price

Total 1 raw suppliers

Chemical Property of 9H-Imidazo(1,2-a)purin-9-one, 3,5-dihydro-3-((2-hydroxyethoxy)methyl)-5,6-dimethyl-

Chemical Property:

Vapor Pressure:5.39E-13mmHg at 25°C
Boiling Point:551.4°Cat760mmHg
Flash Point:287.3°C
Density:1.52g/cm³
XLogP3:-1
Hydrogen Bond Donor Count:1
Hydrogen Bond Acceptor Count:5
Rotatable Bond Count:4
Exact Mass:277.11748936
Heavy Atom Count:20
Complexity:478

Purity/Quality:: 99% ^*data from raw suppliers

Safty Information:

Pictogram(s):
Hazard Codes:

MSDS Files:: SDS file from LookChem

Useful:

Canonical SMILES:CC1=CN2C(=O)C3=C(N=C2N1C)N(C=N3)COCCO

Technology Process of 9H-Imidazo(1,2-a)purin-9-one, 3,5-dihydro-3-((2-hydroxyethoxy)methyl)-5,6-dimethyl-

There total 2 articles about 9H-Imidazo(1,2-a)purin-9-one, 3,5-dihydro-3-((2-hydroxyethoxy)methyl)-5,6-dimethyl- which guide to synthetic route it. The literature collected by LookChem mainly comes from the sharing of users and the free literature resources found by Internet computing technology. We keep the original model of the professional version of literature to make it easier and faster for users to retrieve and use. At the same time, we analyze and calculate the most feasible synthesis route with the highest yield for your reference as below:

synthetic route:

Reference yield:

: 59277-89-3
acycloguanosine

: 114199-20-1
N-2-methyl-9-<(2-hydroxyethoxy)methyl>-1,N-2-isopropenoguanine

Guidance literature:: Multi-step reaction with 2 steps

1: 1.) NaH, 3.) aq. NH₃ / 1) DMF, 15 min; 2) DMF, 30 min; 3) overnight, room temperature

2: 1.) K₂CO₃ / 1) DMF, 30 min; 2) DMF, 45 min

With ammonium hydroxide; sodium hydride; potassium carbonate;
DOI:10.1021/jm00402a017

Reference yield:

6-methyl-3,9-dihydro-3-[(2-hydroxyethoxy)methyl]-9-oxo-5H-imidazol[1,2-a]purine: 114199-19-8
6-methyl-3,9-dihydro-3-[(2-hydroxyethoxy)methyl]-9-oxo-5H-imidazol[1,2-a]purine

: 74-88-4
methyl iodide

: 114199-20-1
N-2-methyl-9-<(2-hydroxyethoxy)methyl>-1,N-2-isopropenoguanine

Guidance literature:: With potassium carbonate; Yield given. Multistep reaction; 1) DMF, 30 min; 2) DMF, 45 min;
DOI:10.1021/jm00402a017

Reference yield:

: 114199-20-1
N-2-methyl-9-<(2-hydroxyethoxy)methyl>-1,N-2-isopropenoguanine

: 81475-45-8
N-2-methyl-9-<(2-hydroxyethoxy)methyl>guanine

Guidance literature:: With ammonium hydroxide; N-Bromosuccinimide; Yield given. Multistep reaction; 1) water, 25 min; 2) room temperature, 30 min;
DOI:10.1021/jm00402a017