SALOR-INT L169811-1EA

Base Information

• Chemical Name: SALOR-INT L169811-1EA
• CAS No.: 59417-06-0
• Molecular Formula: C6H10N2O2
• Molecular Weight: 142.158
• Hs Code.: 2933599090
• Mol file: 59417-06-0.mol

Synonyms:2,3-piperazinedione, 1,4-dimethyl-;N,N'-Dimethyldiketopiperazine

Chemical Property of SALOR-INT L169811-1EA

Chemical Property:

• Vapor Pressure: 0.237mmHg at 25°C
• Melting Point: 176-179 °C
• Refractive Index: 1.491
• Boiling Point: 206.5 °C at 760 mmHg
• PKA: -1.19±0.20(Predicted)
• Flash Point: 81.2 °C
• PSA: 40.62000
• Density: 1.169 g/cm³
• LogP: -1.20740
• Storage Temp.: 2-8°C

Purity/Quality:

1,4-Dimethylpiperazine-2,3-dione 95+% ^*data from reagent suppliers

Safty Information:

• Pictogram(s):  
• Hazard Codes: 

MSDS Files:

SDS file from LookChem

Useful:

Technology Process of SALOR-INT L169811-1EA

There total 6 articles about SALOR-INT L169811-1EA which guide to synthetic route it. The literature collected by LookChem mainly comes from the sharing of users and the free literature resources found by Internet computing technology. We keep the original model of the professional version of literature to make it easier and faster for users to retrieve and use. At the same time, we analyze and calculate the most feasible synthesis route with the highest yield for your reference as below:

synthetic route:

Reference yield: 96.0%

oxalic acid diethyl ester (95-92-1) + N,N`-dimethylethylenediamine (110-70-3) → 1,4-dimethyl-2,3-dioxopiperazine (59417-06-0)

Guidance literature:

In diethyl ether; at 20 ℃;

Reference yield: 90.0%

Dimethyl oxalate (553-90-2) + N,N`-dimethylethylenediamine (110-70-3) → 1,4-dimethyl-2,3-dioxopiperazine (59417-06-0)

Guidance literature:

In diethyl ether; at 25 ℃; for 12h;

DOI:10.1021/ol102237b

Reference yield: 61.0%

N,N'-dimethylpiperazine (106-58-1) → 1,4-dimethyl-2,3-dioxopiperazine (59417-06-0)

Guidance literature:

With [bis(acetoxy)iodo]benzene; iodine; In tetrahydrofuran; at 20 ℃; for 1.5h;

DOI:10.1021/acs.joc.8b01424

upstream raw materials:

oxalic acid diethyl ester

N,N`-dimethylethylenediamine

4,7-Dimethyl-4,5,6,7-tetrahydro-[1,2,5]oxadiazolo[3,4-b]pyrazine 1-oxide

1,4-Dimethyl-piperazine-2,3-dione dioxime

Downstream raw materials:

decane-5,6-dione

Phenyl-1,2-hexanedione

benzil

1-(4-methoxyphenyl)hexane-1,2-dione