2-[(Difluoromethyl)sulfanyl]aniline

Base Information

Chemical Name:2-[(Difluoromethyl)sulfanyl]aniline
CAS No.:24933-58-2
Molecular Formula:C7H7 F2 N S
Molecular Weight:175.2
Hs Code.:2930909090
European Community (EC) Number:691-434-5
DSSTox Substance ID:DTXSID90947814
Wikidata:Q82925635
Mol file:24933-58-2.mol

Synonyms:2-[(difluoromethyl)sulfanyl]aniline;24933-58-2;2-(difluoromethylsulfanyl)aniline;2-((difluoromethyl)thio)aniline;2-[(Difluoromethyl)thio]aniline, HCl;SCHEMBL999078;DTXSID90947814;VNYLLNCVORSDAC-UHFFFAOYSA-N;AKOS008987459;EN300-40736;F2167-4976

Suppliers and Price of 2-[(Difluoromethyl)sulfanyl]aniline

Supply Marketing:

Business phase:: The product has achieved commercial mass production^*data from LookChem market partment

Manufacturers and distributors:

Manufacture/Brand
Chemicals and raw materials
Packaging
price

Crysdot
2-((Difluoromethyl)thio)anilinehydrochloride 97%
1g
$ 564.00

American Custom Chemicals Corporation
2-[(DIFLUOROMETHYL)THIO]ANILINE HYDROCHLORIDE 95.00%
5G
$ 1928.08

American Custom Chemicals Corporation
2-[(DIFLUOROMETHYL)THIO]ANILINE HYDROCHLORIDE 95.00%
2.5G
$ 1473.14

American Custom Chemicals Corporation
2-[(DIFLUOROMETHYL)THIO]ANILINE HYDROCHLORIDE 95.00%
1G
$ 983.52

Total 5 raw suppliers

Chemical Property of 2-[(Difluoromethyl)sulfanyl]aniline

Chemical Property:

Vapor Pressure:0.319mmHg at 25°C
Boiling Point:200.7°Cat760mmHg
PKA:1.48±0.10(Predicted)
Flash Point:75.2°C
PSA：51.32000
Density:1.29g/cm³
LogP:3.96670
XLogP3:2.7
Hydrogen Bond Donor Count:1
Hydrogen Bond Acceptor Count:4
Rotatable Bond Count:2
Exact Mass:175.02672673
Heavy Atom Count:11
Complexity:121

Purity/Quality:

97% ^*data from raw suppliers

2-((Difluoromethyl)thio)anilinehydrochloride 97% ^*data from reagent suppliers

Safty Information:

Pictogram(s):
Hazard Codes:

MSDS Files:: SDS file from LookChem

Useful:

Canonical SMILES:C1=CC=C(C(=C1)N)SC(F)F

Technology Process of 2-[(Difluoromethyl)sulfanyl]aniline

There total 4 articles about 2-[(Difluoromethyl)sulfanyl]aniline which guide to synthetic route it. The literature collected by LookChem mainly comes from the sharing of users and the free literature resources found by Internet computing technology. We keep the original model of the professional version of literature to make it easier and faster for users to retrieve and use. At the same time, we analyze and calculate the most feasible synthesis route with the highest yield for your reference as below:

synthetic route:

Reference yield: 59.0%

: 58310-28-4
(Difluoromethyl)triphenylphosphonium bromide

: 137-07-5
2-amino-benzenethiol

: 24933-58-2
2-((difluoromethyl)thio)aniline

Guidance literature:: With sodium hydride; In N,N-dimethyl-formamide; mineral oil; at 20 ℃; chemoselective reaction; Irradiation;
DOI:10.1021/acs.orglett.7b02109

Reference yield:

: 24933-38-8
(difluoromethyl)(2-nitrophenyl)sulfane

: 24933-58-2
2-((difluoromethyl)thio)aniline

Guidance literature:: With hydrogenchloride; tin(ll) chloride;

Reference yield:

: 1155-00-6
bis(2-nitrophenyl)disulfide

: 24933-58-2
2-((difluoromethyl)thio)aniline

Guidance literature:: Multi-step reaction with 2 steps

1: (i) aq. NaOH, H₂S, (ii) /BRN= 1731036/

2: aq. HCl, SnCl₂

With hydrogenchloride; tin(ll) chloride;