Carbamic acid, [(3S,4S)-3-[(1S)-1-hydroxy-2-methylpropyl]-1-[(1S)-1-(4-methoxyphenyl) ethyl]-2-oxo-4-[2-(trimethylsilyl)-3-furanyl]-3-azetidinyl]-, 1,1-dimethylethyl ester

Base Information

Chemical Name:Carbamic acid, [(3S,4S)-3-[(1S)-1-hydroxy-2-methylpropyl]-1-[(1S)-1-(4-methoxyphenyl) ethyl]-2-oxo-4-[2-(trimethylsilyl)-3-furanyl]-3-azetidinyl]-, 1,1-dimethylethyl ester
CAS No.:870528-58-8
Molecular Formula:C28H42N2O6Si
Molecular Weight:530.737
Hs Code.:

Carbamic acid,
[(3S,4S)-3-[(1S)-1-hydroxy-2-methylpropyl]-1-[(1S)-1-(4-methoxyphenyl)
ethyl]-2-oxo-4-[2-(trimethylsilyl)-3-furanyl]-3-azetidinyl]-, 1,1-dimethylethyl
ester

Synonyms:

Suppliers and Price of Carbamic acid, [(3S,4S)-3-[(1S)-1-hydroxy-2-methylpropyl]-1-[(1S)-1-(4-methoxyphenyl) ethyl]-2-oxo-4-[2-(trimethylsilyl)-3-furanyl]-3-azetidinyl]-, 1,1-dimethylethyl ester

Supply Marketing:

Business phase:: The product has achieved commercial mass production^*data from LookChem market partment

Manufacturers and distributors:

Manufacture/Brand
Chemicals and raw materials
Packaging
price

Total 0 raw suppliers

Chemical Property of Carbamic acid, [(3S,4S)-3-[(1S)-1-hydroxy-2-methylpropyl]-1-[(1S)-1-(4-methoxyphenyl) ethyl]-2-oxo-4-[2-(trimethylsilyl)-3-furanyl]-3-azetidinyl]-, 1,1-dimethylethyl ester

Chemical Property:

Purity/Quality:

Safty Information:

Pictogram(s):
Hazard Codes:

MSDS Files:

Useful:

Technology Process of Carbamic acid, [(3S,4S)-3-[(1S)-1-hydroxy-2-methylpropyl]-1-[(1S)-1-(4-methoxyphenyl) ethyl]-2-oxo-4-[2-(trimethylsilyl)-3-furanyl]-3-azetidinyl]-, 1,1-dimethylethyl ester

There total 10 articles about Carbamic acid, [(3S,4S)-3-[(1S)-1-hydroxy-2-methylpropyl]-1-[(1S)-1-(4-methoxyphenyl) ethyl]-2-oxo-4-[2-(trimethylsilyl)-3-furanyl]-3-azetidinyl]-, 1,1-dimethylethyl ester which guide to synthetic route it. The literature collected by LookChem mainly comes from the sharing of users and the free literature resources found by Internet computing technology. We keep the original model of the professional version of literature to make it easier and faster for users to retrieve and use. At the same time, we analyze and calculate the most feasible synthesis route with the highest yield for your reference as below:

synthetic route:

Reference yield: 94.0%

: 870528-57-7
(3S,4S,8S)-8-Isopropyl-2-[(S)-1-(4-methoxy-phenyl)-ethyl]-1,6-dioxo-3-(2-trimethylsilanyl-furan-3-yl)-7-oxa-2,5-diaza-spiro[3.4]octane-5-carboxylic acid tert-butyl ester

: 870528-58-8
[(3S,4S)-3-((S)-1-Hydroxy-2-methyl-propyl)-1-[(S)-1-(4-methoxy-phenyl)-ethyl]-2-oxo-4-(2-trimethylsilanyl-furan-3-yl)-azetidin-3-yl]-carbamic acid tert-butyl ester

Guidance literature:: With caesium carbonate; In methanol; at 23 ℃; for 2h;
DOI:10.1021/ja056284a

Reference yield:

: 870528-54-4
(4S,5S) 5-isopropyl-2-oxo-oxazolidine-4-carboxylic acid benzyl ester

: 870528-58-8
[(3S,4S)-3-((S)-1-Hydroxy-2-methyl-propyl)-1-[(S)-1-(4-methoxy-phenyl)-ethyl]-2-oxo-4-(2-trimethylsilanyl-furan-3-yl)-azetidin-3-yl]-carbamic acid tert-butyl ester

Guidance literature:: Multi-step reaction with 5 steps

1: 99 percent / triethylamine; 4-(dimethylamino)pyridine / CH₂Cl₂ / 1 h / 23 °C

2: 98 percent / H₂ / Pd/C / ethyl acetate / 6 h / 23 °C

3: 1-chloro-N,N,2-trimethyl-1-propenylamine / CH₂Cl₂ / -78 - 23 °C

4: 240 mg / triethylamine / CH₂Cl₂ / 0.5 h / 23 °C

5: 94 percent / Cs₂CO₃ / methanol / 2 h / 23 °C

With dmap; 1-chloro-1-(dimethylamino)-2-methyl-1-propene; hydrogen; caesium carbonate; triethylamine; palladium on activated charcoal; In methanol; dichloromethane; ethyl acetate;
DOI:10.1021/ja056284a

Reference yield:

: (2S,3S)-2-Azido-4-methyl-3-phenoxycarbonyloxy-pentanoic acid benzyl ester

: 870528-58-8
[(3S,4S)-3-((S)-1-Hydroxy-2-methyl-propyl)-1-[(S)-1-(4-methoxy-phenyl)-ethyl]-2-oxo-4-(2-trimethylsilanyl-furan-3-yl)-azetidin-3-yl]-carbamic acid tert-butyl ester

Guidance literature:: Multi-step reaction with 6 steps

1: 1.85 g / triphenylphosphine / tetrahydrofuran; H₂O / 1 h / 50 °C

2: 99 percent / triethylamine; 4-(dimethylamino)pyridine / CH₂Cl₂ / 1 h / 23 °C

3: 98 percent / H₂ / Pd/C / ethyl acetate / 6 h / 23 °C

4: 1-chloro-N,N,2-trimethyl-1-propenylamine / CH₂Cl₂ / -78 - 23 °C

5: 240 mg / triethylamine / CH₂Cl₂ / 0.5 h / 23 °C

6: 94 percent / Cs₂CO₃ / methanol / 2 h / 23 °C

With dmap; 1-chloro-1-(dimethylamino)-2-methyl-1-propene; hydrogen; caesium carbonate; triethylamine; triphenylphosphine; palladium on activated charcoal; In tetrahydrofuran; methanol; dichloromethane; water; ethyl acetate;
DOI:10.1021/ja056284a