(2S)-2-[[(2S)-2-amino-3-(3-fluorophenyl)propanoyl]amino]propanoic acid

Base Information

Chemical Name:(2S)-2-[[(2S)-2-amino-3-(3-fluorophenyl)propanoyl]amino]propanoic acid
CAS No.:87184-20-1
Molecular Formula:C12H15FN2O3
Molecular Weight:254.261
Hs Code.:
DSSTox Substance ID:DTXSID80424301
Wikidata:Q82236821
ChEMBL ID:CHEMBL48501

Synonyms:(2S)-2-[[(2S)-2-amino-3-(3-fluorophenyl)propanoyl]amino]propanoic acid;L-m-FPhe-L-Ala;87184-20-1;CHEMBL48501;l-m-fluorophenylalanyl-l-alanine;DTXSID80424301

Suppliers and Price of (2S)-2-[[(2S)-2-amino-3-(3-fluorophenyl)propanoyl]amino]propanoic acid

Supply Marketing:

Business phase:: The product has achieved commercial mass production^*data from LookChem market partment

Manufacturers and distributors:

Manufacture/Brand
Chemicals and raw materials
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Total 0 raw suppliers

Chemical Property of (2S)-2-[[(2S)-2-amino-3-(3-fluorophenyl)propanoyl]amino]propanoic acid

Chemical Property:

XLogP3:-2.8
Hydrogen Bond Donor Count:3
Hydrogen Bond Acceptor Count:5
Rotatable Bond Count:5
Exact Mass:254.10667051
Heavy Atom Count:18
Complexity:312

Purity/Quality:

Safty Information:

Pictogram(s):
Hazard Codes:

MSDS Files:: SDS file from LookChem

Useful:

Canonical SMILES:CC(C(=O)O)NC(=O)C(CC1=CC(=CC=C1)F)N
Isomeric SMILES:C[C@@H](C(=O)O)NC(=O)[C@H](CC1=CC(=CC=C1)F)N

Technology Process of (2S)-2-[[(2S)-2-amino-3-(3-fluorophenyl)propanoyl]amino]propanoic acid

There total 4 articles about (2S)-2-[[(2S)-2-amino-3-(3-fluorophenyl)propanoyl]amino]propanoic acid which guide to synthetic route it. The literature collected by LookChem mainly comes from the sharing of users and the free literature resources found by Internet computing technology. We keep the original model of the professional version of literature to make it easier and faster for users to retrieve and use. At the same time, we analyze and calculate the most feasible synthesis route with the highest yield for your reference as below:

synthetic route:

Reference yield: 75.0%

: 87184-30-3
Cbz-L-m-FPhe-L-Ala-OBzl

: 87184-20-1
L-m-FPhe-L-Ala

Guidance literature:: With methanol; cyclohexene; palladium on activated charcoal; for 3h; Heating;
DOI:10.1021/jm00366a013

Reference yield:

: 49759-64-0
Cbz-L-m-FPhe

: 87184-20-1
L-m-FPhe-L-Ala

Guidance literature:: Multi-step reaction with 2 steps

1: 65 percent / N-ethylmorpholine, hydroxybenzotriazole, DCC / dimethylformamide / 1.) 5-10 deg C, 1 h, 2.) 27 deg C, 2 h

2: 75 percent / CH₃OH, cyclohexene / 10percent Pd/C / 3 h / Heating

With N-ethylmorpholine;; methanol; benzotriazol-1-ol; dicyclohexyl-carbodiimide; cyclohexene; palladium on activated charcoal; In N,N-dimethyl-formamide;
DOI:10.1021/jm00366a013