3-(Benzyloxy)-7-fluoro-10H-phenothiazine

Base Information

Chemical Name:3-(Benzyloxy)-7-fluoro-10H-phenothiazine
CAS No.:87216-37-3
Molecular Formula:C₁₉H₁₄FNOS
Molecular Weight:323.391
Hs Code.:
DSSTox Substance ID:DTXSID50520940
Wikidata:Q82385124

Synonyms:87216-37-3;3-(BENZYLOXY)-7-FLUORO-10H-PHENOTHIAZINE;DTXSID50520940

Suppliers and Price of 3-(Benzyloxy)-7-fluoro-10H-phenothiazine

Supply Marketing:

Business phase:: The product has achieved commercial mass production^*data from LookChem market partment

Manufacturers and distributors:

Manufacture/Brand
Chemicals and raw materials
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price

Total 0 raw suppliers

Chemical Property of 3-(Benzyloxy)-7-fluoro-10H-phenothiazine

Chemical Property:

PSA：46.56000
LogP:5.75090
XLogP3:5.2
Hydrogen Bond Donor Count:1
Hydrogen Bond Acceptor Count:4
Rotatable Bond Count:3
Exact Mass:323.07801341
Heavy Atom Count:23
Complexity:390

Purity/Quality:

Safty Information:

Pictogram(s):
Hazard Codes:

MSDS Files:: SDS file from LookChem

Useful:

Canonical SMILES:C1=CC=C(C=C1)COC2=CC3=C(C=C2)NC4=C(S3)C=C(C=C4)F

Technology Process of 3-(Benzyloxy)-7-fluoro-10H-phenothiazine

There total 3 articles about 3-(Benzyloxy)-7-fluoro-10H-phenothiazine which guide to synthetic route it. The literature collected by LookChem mainly comes from the sharing of users and the free literature resources found by Internet computing technology. We keep the original model of the professional version of literature to make it easier and faster for users to retrieve and use. At the same time, we analyze and calculate the most feasible synthesis route with the highest yield for your reference as below:

synthetic route:

Reference yield:

: 52969-98-9
2-amino-5-fluorobenzenethiol zinc salt

: 87216-37-3
3-benzyloxy-7-fluorophenothiazine

Guidance literature:: Multi-step reaction with 2 steps

1: 73 percent / NaOH, oxygen / ethanol; H₂O / 1 h / Heating

2: 1.) potassium carbonate; / 1.) acetone, reflux, 0.5 h; 2) reflux, 8 h

With sodium hydroxide; oxygen; potassium carbonate; In ethanol; water;
DOI:10.1002/jhet.5570200360

Reference yield:

: 615-67-8
chloro-p-hydroquinone

: 87216-37-3
3-benzyloxy-7-fluorophenothiazine

Guidance literature:: Multi-step reaction with 2 steps

1: 73 percent / NaOH, oxygen / ethanol; H₂O / 1 h / Heating

2: 1.) potassium carbonate; / 1.) acetone, reflux, 0.5 h; 2) reflux, 8 h

With sodium hydroxide; oxygen; potassium carbonate; In ethanol; water;
DOI:10.1002/jhet.5570200360

Reference yield:

: 100-39-0
benzyl bromide

: 35986-23-3
7-fluorophenothiazin-3-ol

: 87216-37-3
3-benzyloxy-7-fluorophenothiazine

Guidance literature:: With potassium carbonate; Yield given. Multistep reaction; 1.) acetone, reflux, 0.5 h; 2) reflux, 8 h;
DOI:10.1002/jhet.5570200360