4-Fluoro-3-methoxycarbonylphenylboronic acid pinacol ester

Base Information

Chemical Name:4-Fluoro-3-methoxycarbonylphenylboronic acid pinacol ester
CAS No.:872459-87-5
Molecular Formula:C14H18BFO4
Molecular Weight:280.104
Hs Code.:
Mol file:872459-87-5.mol

Synonyms:2-FLUORO-5-(4,4,5,5-TETRAMETHYL-1,3,2-DIOXABOROLAN-2-YL)-BENZOIC ACID,METHYL ESTER;4-FLUORO-3-(METHOXYCORBONYL)PHENYLBORONIC ACID PINACOL ESTER;BENZOIC ACID,2-FLUORO-5-(4,4,5,5-TETRAMETHYL-1,3,2-DIOXABOROLAN-2-YL)-,METHYL ESTER;4-FLUORO-3-(METHOXYCORBONYL)BENZENEBORONIC ACID PINACOL ESTER;

Suppliers and Price of 4-Fluoro-3-methoxycarbonylphenylboronic acid pinacol ester

Supply Marketing:

Business phase:: The product has achieved commercial mass production^*data from LookChem market partment

Manufacturers and distributors:

Manufacture/Brand
Chemicals and raw materials
Packaging
price

Crysdot
Methyl2-fluoro-5-(4,4,5,5-tetramethyl-1,3,2-dioxaborolan-2-yl)benzoate 97%
5g
$ 675.00

Crysdot
Methyl2-fluoro-5-(4,4,5,5-tetramethyl-1,3,2-dioxaborolan-2-yl)benzoate 97%
1g
$ 225.00

Chemenu
Methyl2-fluoro-5-(4,4,5,5-tetramethyl-1,3,2-dioxaborolan-2-yl)benzoate 97%
1g
$ 163.00

AOBChem
4-Fluoro-3-methoxycarbonylphenylboronicacidpinacolester 97%
100g
$ 4000.00

AOBChem
4-Fluoro-3-methoxycarbonylphenylboronicacidpinacolester 97%
10g
$ 736.00

AOBChem
4-Fluoro-3-methoxycarbonylphenylboronicacidpinacolester 97%
5g
$ 432.00

Total 6 raw suppliers

Chemical Property of 4-Fluoro-3-methoxycarbonylphenylboronic acid pinacol ester

Chemical Property:

Boiling Point:368.5±37.0 °C(Predicted)
PSA：44.76000
Density:1.14±0.1 g/cm3(Predicted)
LogP:1.91150

Purity/Quality:

99%,98%, ^*data from raw suppliers

Methyl2-fluoro-5-(4,4,5,5-tetramethyl-1,3,2-dioxaborolan-2-yl)benzoate 97% ^*data from reagent suppliers

Safty Information:

Pictogram(s):
Hazard Codes:

MSDS Files:: SDS file from LookChem

Useful:

Uses 4-Fluoro-3-Methoxycarbonylphenylboronic Acid Pinacol Ester is used in preparation of Biphenyl Pyridazinone derivatives as inhaled PDE4 inhibitors in relation to structural biology and structure-activity relationships.

Technology Process of 4-Fluoro-3-methoxycarbonylphenylboronic acid pinacol ester

There total 3 articles about 4-Fluoro-3-methoxycarbonylphenylboronic acid pinacol ester which guide to synthetic route it. The literature collected by LookChem mainly comes from the sharing of users and the free literature resources found by Internet computing technology. We keep the original model of the professional version of literature to make it easier and faster for users to retrieve and use. At the same time, we analyze and calculate the most feasible synthesis route with the highest yield for your reference as below:

synthetic route:

Reference yield:

: 57381-59-6
methyl 2-fluoro-5-bromobenzoate

: 73183-34-3
bis(pinacol)diborane

: 872459-87-5
methyl-2-fluoro-5-(4,4,5,5-tetramethyl-1,3,2-dioxaborolan-2-yl)benzoate

Guidance literature:: With potassium acetate; 1,1'-bis-(diphenylphosphino)ferrocene; (1,1'-bis(diphenylphosphino)ferrocene)palladium(II) dichloride; In N,N-dimethyl-formamide; at 90 ℃; for 18h;

Reference yield:

: C₁₄H₆F₆O₅S

: 25015-63-8
4,4,5,5-tetramethyl-[1,3,2]-dioxaboralane

: 872459-87-5
methyl-2-fluoro-5-(4,4,5,5-tetramethyl-1,3,2-dioxaborolan-2-yl)benzoate

Guidance literature:: With bis-triphenylphosphine-palladium(II) chloride; potassium acetate; In toluene; for 3h; Inert atmosphere; Schlenk technique;
DOI:10.1016/j.tetlet.2015.07.033