2-Methyl-1-[(4-nitrophenyl)sulfonyl]pyrrolidine

Base Information

Chemical Name:2-Methyl-1-[(4-nitrophenyl)sulfonyl]pyrrolidine
CAS No.:875930-44-2
Molecular Formula:C₁₁H₁₄N₂O₄S
Molecular Weight:270.309
Hs Code.:
DSSTox Substance ID:DTXSID40698561
Nikkaji Number:J2.244.429H
Mol file:875930-44-2.mol

Synonyms:875930-44-2;2-METHYL-1-[(4-NITROPHENYL)SULFONYL]PYRROLIDINE;2-Methyl-1-((4-nitrophenyl)sulfonyl)pyrrolidine;DTXSID40698561;1-(4-Nitrophenylsulfonyl)-2-methylpyrrolidine;2-Methyl-1-(4-nitrobenzene-1-sulfonyl)pyrrolidine

Suppliers and Price of 2-Methyl-1-[(4-nitrophenyl)sulfonyl]pyrrolidine

Supply Marketing:

Business phase:: The product has achieved commercial mass production^*data from LookChem market partment

Manufacturers and distributors:

Manufacture/Brand
Chemicals and raw materials
Packaging
price

American Custom Chemicals Corporation
2-METHYL-1-[(4-NITROPHENYL)SULFONYL]PYRROLIDINE 95.00%
5MG
$ 505.14

Total 1 raw suppliers

Chemical Property of 2-Methyl-1-[(4-nitrophenyl)sulfonyl]pyrrolidine

Chemical Property:

PSA：91.58000
LogP:3.30970
XLogP3:1.8
Hydrogen Bond Donor Count:0
Hydrogen Bond Acceptor Count:5
Rotatable Bond Count:2
Exact Mass:270.06742811
Heavy Atom Count:18
Complexity:404

Purity/Quality:: 2-METHYL-1-[(4-NITROPHENYL)SULFONYL]PYRROLIDINE 95.00% ^*data from reagent suppliers

Safty Information:

Pictogram(s):
Hazard Codes:

MSDS Files:: SDS file from LookChem

Useful:

Canonical SMILES:CC1CCCN1S(=O)(=O)C2=CC=C(C=C2)[N+](=O)[O-]

Technology Process of 2-Methyl-1-[(4-nitrophenyl)sulfonyl]pyrrolidine

There total 4 articles about 2-Methyl-1-[(4-nitrophenyl)sulfonyl]pyrrolidine which guide to synthetic route it. The literature collected by LookChem mainly comes from the sharing of users and the free literature resources found by Internet computing technology. We keep the original model of the professional version of literature to make it easier and faster for users to retrieve and use. At the same time, we analyze and calculate the most feasible synthesis route with the highest yield for your reference as below:

synthetic route:

Reference yield: 92.0%

: 544-97-8
dimethyl zinc(II)

: C₁₂H₁₃F₃N₂O₅S

: 875930-44-2
2-methyl-1-(4-nitro-benzenesulfonyl)-pyrrolidine

Guidance literature:: With boron trifluoride diethyl etherate; In n-heptane; acetonitrile; at 0 ℃; for 1h; Inert atmosphere;
DOI:10.1021/jacs.1c09412

Reference yield: 70.0%

: C₂₉H₃₀O₂P₂

: 6325-93-5
p-nitrobenzenesulfonamide

: 875930-44-2
2-methyl-1-(4-nitro-benzenesulfonyl)-pyrrolidine

Guidance literature:: With 1-Azidoadamantane; In various solvent(s); at 80 ℃; for 6h;
DOI:10.1246/cl.2005.1644

Reference yield: 54.0%

: 75-24-1
trimethylaluminum

: 175278-37-2
1-((4-nitrophenyl)sulfonyl)pyrrolidine

: 875930-44-2
2-methyl-1-(4-nitro-benzenesulfonyl)-pyrrolidine

Guidance literature:: 1-((4-nitrophenyl)sulfonyl)pyrrolidine; With dihydrogen peroxide; C₄₀H₃₆F₁₂MnN₆⁽²⁺⁾*2F₆Sb^(1-); acetic acid; In acetonitrile; at -36 ℃; for 1h;

trimethylaluminum; With boron trifluoride diethyl etherate; In dichloromethane; at -78 - 20 ℃; for 4h; regioselective reaction;
DOI:10.1038/s41586-020-2137-8