Ethyl N-hydroxyacetimidate

Base Information

• Chemical Name: Ethyl N-hydroxyacetimidate
• CAS No.: 10576-12-2
• Molecular Formula: C4H9NO2
• Molecular Weight: 103.121
• Hs Code.: 29280000
• European Community (EC) Number: 234-165-7
• NSC Number: 255004
• Nikkaji Number: J226.999F
• Mol file: 10576-12-2.mol

Synonyms:ethyl acetohydroximate

Chemical Property of Ethyl N-hydroxyacetimidate

Chemical Property:

• Appearance/Colour: clear colorless liquid after melting
• Vapor Pressure: 0.663mmHg at 25°C
• Melting Point: 23-25 °C(lit.)
• Refractive Index: n20/D 1.434(lit.)
• Boiling Point: 164.478 °C at 760 mmHg
• PKA: 14.20±0.10(Predicted)
• Flash Point: 76.667 °C
• PSA: 41.82000
• Density: 0.999 g/cm³
• LogP: 0.83050
• Storage Temp.: 2-8°C
• Sensitive.: Moisture Sensitive
• Water Solubility.: may decompose
• XLogP3: 0.7
• Hydrogen Bond Donor Count: 1
• Hydrogen Bond Acceptor Count: 3
• Rotatable Bond Count: 2
• Exact Mass: 103.063328530
• Heavy Atom Count: 7
• Complexity: 70.1

Purity/Quality:

99% ^*data from raw suppliers

Ethyl Acetohydroximate >95.0%(GC) ^*data from reagent suppliers

Safty Information:

• Pictogram(s): Xi
• Hazard Codes: Xi
• Statements: 10-36/37/38
• Safety Statements: 37/39-26-37

MSDS Files:

SDS file from LookChem

Total 1 MSDS from other Authors

Useful:

• Canonical SMILES: CCOC(=NO)C
• Isomeric SMILES: CCO/C(=N\O)/C
• Uses: Ethyl N-hydroxyacetimidate was used in the synthesis of O-acyl-and O-nitrophenylhydroxylamines, hydroxamic acid ethoxycarbonylhydrazides and ethyl O-(2,4-dinitrophenyl)acetohydroxamate. Ethyl acetohydroxamate was used in the synthesis of:O-acyl-and O-nitrophenylhydroxylamineshydroxamic acid ethoxycarbonylhydrazidesethyl O-(2,4-dinitrophenyl)acetohydroxamate

Technology Process of Ethyl N-hydroxyacetimidate

There total 4 articles about Ethyl N-hydroxyacetimidate which guide to synthetic route it. The literature collected by LookChem mainly comes from the sharing of users and the free literature resources found by Internet computing technology. We keep the original model of the professional version of literature to make it easier and faster for users to retrieve and use. At the same time, we analyze and calculate the most feasible synthesis route with the highest yield for your reference as below:

synthetic route:

Reference yield: 65.0%

O-ethyl acetimidate (1000-84-6) → ethyl acetohydroximate (10576-12-2)

Guidance literature:

With hydroxylamine hydrochloride; potassium carbonate; In diethyl ether; water; for 0.5h;

DOI:10.1002/hlca.19860690522

Reference yield:

ethyl acetimidate hydrochloride (2208-07-3) → ethyl acetohydroximate (10576-12-2)

Guidance literature:

With hydroxylamine hydrochloride; potassium carbonate;

Reference yield:

ethanol (64-17-5) + acetonitrile (75-05-8,26809-02-9) → ethyl acetohydroximate (10576-12-2)

Guidance literature:

Multistep reaction; (i) HCl, (ii) benzene, (iii) aq. NaOH, NH₂OH*HCl, NaOEt;

DOI:10.1007/BF00906825

upstream raw materials:

O-ethyl acetimidate

ethyl acetimidate hydrochloride

ethanol

acetonitrile

Downstream raw materials:

O-[3-(3-methylphenoxy)-2-hydroxypropyl]-hydroxylamine

O-p-Methoxy-benzylacethydroximsaeure-aethylester

C₆H₈F₃NO₃

ethyl-N-methoxy-acetimidate

Refernces