Androstane

Base Information

Chemical Name:Androstane
CAS No.:24887-75-0
Deprecated CAS:28805-72-3
Molecular Formula:C₁₉H₃₂
Molecular Weight:260.463
Hs Code.:
DSSTox Substance ID:DTXSID40179587
Nikkaji Number:J39.511K
Wikipedia:Androstane
Wikidata:Q2846975
Metabolomics Workbench ID:55120
Mol file:24887-75-0.mol

Synonyms:5 alpha-androstane;androstane;androstane, (5alpha)-isomer;androstane, (5beta)-isomer

Suppliers and Price of Androstane

Supply Marketing:

Business phase:: The product has achieved commercial mass production^*data from LookChem market partment

Manufacturers and distributors:

Manufacture/Brand
Chemicals and raw materials
Packaging
price

Total 3 raw suppliers

Chemical Property of Androstane

Chemical Property:

Vapor Pressure:0.000224mmHg at 25°C
Melting Point:50°C
Refractive Index:1.4750 (estimate)
Boiling Point:336°Cat760mmHg
Flash Point:145.9°C
PSA：0.00000
Density:0.95g/cm³
LogP:5.80930
XLogP3:7.6
Hydrogen Bond Donor Count:0
Hydrogen Bond Acceptor Count:0
Rotatable Bond Count:0
Exact Mass:260.250401021
Heavy Atom Count:19
Complexity:359

Purity/Quality:: 99% ^*data from raw suppliers

Safty Information:

Pictogram(s):
Hazard Codes:

MSDS Files:: SDS file from LookChem

Useful:

Chemical Classes:Other Uses -> Biochemical Research
Canonical SMILES:CC12CCCC1C3CCC4CCCCC4(C3CC2)C
Isomeric SMILES:C[C@@]12CCC[C@H]1[C@@H]3CCC4CCCC[C@@]4([C@H]3CC2)C

Technology Process of Androstane

There total 23 articles about Androstane which guide to synthetic route it. The literature collected by LookChem mainly comes from the sharing of users and the free literature resources found by Internet computing technology. We keep the original model of the professional version of literature to make it easier and faster for users to retrieve and use. At the same time, we analyze and calculate the most feasible synthesis route with the highest yield for your reference as below:

synthetic route:

Reference yield: 81.0%

: 13β,14β-methano-18-nor-5α-androstane

: 438-22-2,438-23-3,1757-51-3,3986-82-1,4030-91-5,10085-13-9,13077-81-1,15885-55-9,22511-92-8,24887-75-0,35457-05-7,28805-72-3
5α,14β-androstane

Guidance literature:: With triethylsilane; trifluoroacetic acid; In dichloromethane; at -20 ℃; for 2h;
DOI:10.1002/chem.201502148

Reference yield:

: 81827-60-3
Trifluoro-methanesulfonic acid (8R,9S,10S,13S,14S)-10,13-dimethyl-3-trifluoromethanesulfonyloxy-4,5,6,7,8,9,10,11,12,13,14,15-dodecahydro-1H-cyclopenta[a]phenanthren-17-yl ester

: 24887-75-0,28805-72-3
androstane

Guidance literature:: With hydrogen; platinum(IV) oxide; In ethanol; under 760 Torr; Yield given; Ambient temperature;
DOI:10.1016/S0040-4039(00)97549-X

Reference yield:

: 5982-99-0
androstane-3,17-dione

: 24887-75-0,28805-72-3
androstane

Guidance literature:: Multi-step reaction with 2 steps

1: 2,6-di-t-butyl-4-methylpyridine / CH₂Cl₂ / Heating

2: H₂ / PtO₂ / ethanol / 760 Torr / Ambient temperature

With 2,6-di-tert-butyl-4-methylpyridine; hydrogen; platinum(IV) oxide; In ethanol; dichloromethane;
DOI:10.1016/S0040-4039(00)97549-X