11,19-Oxidoprogesterone

Base Information

Chemical Name:11,19-Oxidoprogesterone
CAS No.:1913-28-6
Molecular Formula:C₂₁H₂₈O₃
Molecular Weight:328.452
Hs Code.:
Mol file:1913-28-6.mol

Synonyms:11,19-oxidoprogesterone

Suppliers and Price of 11,19-Oxidoprogesterone

Supply Marketing:

Business phase:: The product has achieved commercial mass production^*data from LookChem market partment

Manufacturers and distributors:

Manufacture/Brand
Chemicals and raw materials
Packaging
price

Total 6 raw suppliers

Chemical Property of 11,19-Oxidoprogesterone

Chemical Property:

Vapor Pressure:6.98E-10mmHg at 25°C
Boiling Point:493.5°C at 760 mmHg
Flash Point:216.8°C
PSA：43.37000
Density:1.18g/cm³
LogP:3.71230
XLogP3:2.4
Hydrogen Bond Donor Count:0
Hydrogen Bond Acceptor Count:3
Rotatable Bond Count:1
Exact Mass:328.20384475
Heavy Atom Count:24
Complexity:650

Purity/Quality:: 98%,99%, ^*data from raw suppliers

Safty Information:

Pictogram(s):
Hazard Codes:

MSDS Files:: SDS file from LookChem

Useful:

Canonical SMILES:CC(=O)C1CCC2C1(CC3C4C2CCC5=CC(=O)CCC45CO3)C
Isomeric SMILES:CC(=O)[C@H]1CC[C@@H]2[C@@]1(CC3[C@H]4[C@H]2CCC5=CC(=O)CC[C@]45CO3)C

Technology Process of 11,19-Oxidoprogesterone

There total 11 articles about 11,19-Oxidoprogesterone which guide to synthetic route it. The literature collected by LookChem mainly comes from the sharing of users and the free literature resources found by Internet computing technology. We keep the original model of the professional version of literature to make it easier and faster for users to retrieve and use. At the same time, we analyze and calculate the most feasible synthesis route with the highest yield for your reference as below:

synthetic route:

Reference yield:

: 1905-53-9
11,19-Oxidopregn-5-ene-3,20-dione

: 1913-28-6
11,19-Oxidopregn-4-ene-3,20-dione

Guidance literature:: With hydrogenchloride; In methanol; dichloromethane; at 25 ℃; for 16h;

Reference yield:

: 516-15-4
11-Ketoprogesterone

: 1913-28-6
11,19-Oxidopregn-4-ene-3,20-dione

Guidance literature:: Multi-step reaction with 9 steps

1: 2.3 g / 4 h / 70 - 75 °C

3: 3.1 g / 7.5percent aq. perchloric acid, N-bromoacetamide / diethyl ether; tetrahydrofuran / 0.5 h / Ambient temperature

4: 2.9 g / red mercuric oxide, iodine / CCl₄ / 0.5 h / 25 °C / Irradiation

5: zinc, iodine / acetic acid; H₂O / 5 h / 75 °C

6: 687 mg / sodium cyanoborohydride / methanol / 25 °C / pH 2-3

7: 164 mg / lithium aluminium hydride / tetrahydrofuran / 5 h / Heating

8: 92 mg / pyridinium dichromate, molecular sieves (3 Angstroem) / CH₂Cl₂ / 24 h / 25 °C

9: 92 mg / aq. HCl / CH₂Cl₂; methanol / 16 h / 25 °C

With hydrogenchloride; lithium aluminium tetrahydride; dipyridinium dichromate; perchloric acid; 3 A molecular sieve; iodine; sodium cyanoborohydride; mercury(II) oxide; zinc; N-bromoacetamide; In tetrahydrofuran; methanol; tetrachloromethane; diethyl ether; dichloromethane; water; acetic acid;

Reference yield:

: 38368-22-8
(8S,9S,10R,13S,14S,17S)-17-acetyl-10,13-dimethyl-11-oxo-2,7,8,9,10,11,12,13,14,15,16,17-dodecahydro-1H-cyclopenta[a]phenanthren-3-yl acetate

: 1913-28-6
11,19-Oxidopregn-4-ene-3,20-dione

Guidance literature:: Multi-step reaction with 8 steps

2: 3.1 g / 7.5percent aq. perchloric acid, N-bromoacetamide / diethyl ether; tetrahydrofuran / 0.5 h / Ambient temperature

3: 2.9 g / red mercuric oxide, iodine / CCl₄ / 0.5 h / 25 °C / Irradiation

4: zinc, iodine / acetic acid; H₂O / 5 h / 75 °C

5: 687 mg / sodium cyanoborohydride / methanol / 25 °C / pH 2-3

6: 164 mg / lithium aluminium hydride / tetrahydrofuran / 5 h / Heating

7: 92 mg / pyridinium dichromate, molecular sieves (3 Angstroem) / CH₂Cl₂ / 24 h / 25 °C

8: 92 mg / aq. HCl / CH₂Cl₂; methanol / 16 h / 25 °C

With hydrogenchloride; lithium aluminium tetrahydride; dipyridinium dichromate; perchloric acid; 3 A molecular sieve; iodine; sodium cyanoborohydride; mercury(II) oxide; zinc; N-bromoacetamide; In tetrahydrofuran; methanol; tetrachloromethane; diethyl ether; dichloromethane; water; acetic acid;