3-Methoxyacridin-9-one

Base Information

• Chemical Name: 3-Methoxyacridin-9-one
• CAS No.: 61736-68-3
• Molecular Formula: C14H11NO2
• Molecular Weight: 225.247
• Hs Code.: 2933990090
• DSSTox Substance ID: DTXSID90210737
• Nikkaji Number: J346.080K
• Wikidata: Q83085497
• ChEMBL ID: CHEMBL1210587
• Mol file: 61736-68-3.mol

Synonyms:3-methoxyacridin-9-one;MO-A-9

Chemical Property of 3-Methoxyacridin-9-one

Chemical Property:

• Vapor Pressure: 1.04E-06mmHg at 25°C
• Boiling Point: 403.2°Cat760mmHg
• Flash Point: 197.6°C
• PSA: 42.09000
• Density: 1.233g/cm³
• LogP: 2.68990
• XLogP3: 2.9
• Hydrogen Bond Donor Count: 1
• Hydrogen Bond Acceptor Count: 3
• Rotatable Bond Count: 1
• Exact Mass: 225.078978594
• Heavy Atom Count: 17
• Complexity: 305

Purity/Quality:

Safty Information:

• Pictogram(s):  
• Hazard Codes: 

MSDS Files:

SDS file from LookChem

Useful:

• Canonical SMILES: COC1=CC2=C(C=C1)C(=O)C3=CC=CC=C3N2

Technology Process of 3-Methoxyacridin-9-one

There total 22 articles about 3-Methoxyacridin-9-one which guide to synthetic route it. The literature collected by LookChem mainly comes from the sharing of users and the free literature resources found by Internet computing technology. We keep the original model of the professional version of literature to make it easier and faster for users to retrieve and use. At the same time, we analyze and calculate the most feasible synthesis route with the highest yield for your reference as below:

synthetic route:

Reference yield: 65.0%

5-methoxydiphenylamine-2-carboxylic acid (19218-83-8) → 3-methoxyacridine-9(10H)-one (61736-68-3)

Guidance literature:

With sulfuric acid; at 100 ℃;

DOI:10.1021/jo00324a025

Reference yield: 56.0%

2-amino-4'-methoxybenzophenone (36192-61-7) → 3-methoxyacridine-9(10H)-one (61736-68-3)

Guidance literature:

With potassium tert-butylate; In dimethyl sulfoxide; at 20 ℃; for 12h;

DOI:10.1002/adsc.201701579

Reference yield: 52.0%

6-methoxybenzo[c]isoxazole + phenylboronic acid (98-80-6) → 3-methoxyacridine-9(10H)-one (61736-68-3)

Guidance literature:

With copper(l) iodide; silver(l) oxide; In dimethyl sulfoxide; chlorobenzene; at 150 ℃; for 24h; Schlenk technique;

DOI:10.1039/d1ob01586a

upstream raw materials:

9-chloro-3-methoxyacridine

5-methoxydiphenylamine-2-carboxylic acid

3-(4-methoxyphenyl)benzo[c]isoxazole

2-methyl-4-oxo-3,1-benzoxazine