- Chemical Name:Unii-97F7ble97S
- CAS No.:941-55-9
- Deprecated CAS:67842-69-7,1647111-45-2
- Molecular Formula:C7H7N3O2S
- Molecular Weight:197.217
- Hs Code.:29299090
- Mol file:941-55-9.mol
Synonyms:UNII-97F7BLE97S;97F7BLE97S;EINECS 213-381-5;NSC 138649
Synonyms:UNII-97F7BLE97S;97F7BLE97S;EINECS 213-381-5;NSC 138649
99% *data from raw suppliers
Tosyl azide, 30% w/w in toluene 95% *data from reagent suppliers
There total 19 articles about Unii-97F7ble97S which guide to synthetic route it. The literature collected by LookChem mainly comes from the sharing of users and the free literature resources found by Internet computing technology. We keep the original model of the professional version of literature to make it easier and faster for users to retrieve and use. At the same time, we analyze and calculate the most feasible synthesis route with the highest yield for your reference as below:
Reference yield: 100.0%
Reference yield: 98.0%
Reference yield: 97.0%
N-[1-Chloro-2-methyl-prop-(Z)-ylidene]-4-methyl-benzenesulfonamide
The study focuses on the synthesis of substituted 2-azabicyclo[3.2.1]octadienes, which are significant in the creation of natural products and biologically active compounds, through the ring expansion of substituted norbornadienes using toluenesulfonyl azide. The researchers explored the regioselectivity of the cycloaddition/rearrangement process with various mono- and disubstituted norbornadienes, finding that both types could be converted into the bicyclooctadiene ring system with high regiocontrol and in moderate to excellent yields. The study also investigated the impact of different substituent groups on the reaction's outcome, noting that electron-withdrawing groups resulted in little to no product, while hydroxymethyl derivatives provided a moderate yield of a single regioisomer. The synthesized 2-azabicyclo[3.2.1]octadienes can be further modified to yield highly substituted derivatives of the 2-azabicyclo[3.2.1]octane ring system, which is prevalent in natural products and pharmacologically active molecules, thus providing a valuable route for the synthesis of these complex structures.