1-Piperidinecarboxylic acid, 2-[(1S,2S)-2-[(3,5-difluorophenyl)methyl]-1-hydroxy-3-oxo-3-[(4S)-2-oxo -4-(phenylmethyl)-3-oxazolidinyl]propyl]-, 1,1-dimethylethyl ester

Base Information

Chemical Name:1-Piperidinecarboxylic acid, 2-[(1S,2S)-2-[(3,5-difluorophenyl)methyl]-1-hydroxy-3-oxo-3-[(4S)-2-oxo -4-(phenylmethyl)-3-oxazolidinyl]propyl]-, 1,1-dimethylethyl ester
CAS No.:877078-73-4
Molecular Formula:C30H36F2N2O6
Molecular Weight:558.622
Hs Code.:

1-Piperidinecarboxylic acid,
2-[(1S,2S)-2-[(3,5-difluorophenyl)methyl]-1-hydroxy-3-oxo-3-[(4S)-2-oxo
-4-(phenylmethyl)-3-oxazolidinyl]propyl]-, 1,1-dimethylethyl ester

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Business phase:: The product has achieved commercial mass production^*data from LookChem market partment

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Chemical Property of 1-Piperidinecarboxylic acid, 2-[(1S,2S)-2-[(3,5-difluorophenyl)methyl]-1-hydroxy-3-oxo-3-[(4S)-2-oxo -4-(phenylmethyl)-3-oxazolidinyl]propyl]-, 1,1-dimethylethyl ester

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Technology Process of 1-Piperidinecarboxylic acid, 2-[(1S,2S)-2-[(3,5-difluorophenyl)methyl]-1-hydroxy-3-oxo-3-[(4S)-2-oxo -4-(phenylmethyl)-3-oxazolidinyl]propyl]-, 1,1-dimethylethyl ester

There total 1 articles about 1-Piperidinecarboxylic acid, 2-[(1S,2S)-2-[(3,5-difluorophenyl)methyl]-1-hydroxy-3-oxo-3-[(4S)-2-oxo -4-(phenylmethyl)-3-oxazolidinyl]propyl]-, 1,1-dimethylethyl ester which guide to synthetic route it. The literature collected by LookChem mainly comes from the sharing of users and the free literature resources found by Internet computing technology. We keep the original model of the professional version of literature to make it easier and faster for users to retrieve and use. At the same time, we analyze and calculate the most feasible synthesis route with the highest yield for your reference as below:

synthetic route:

Reference yield:

: 877078-49-4
(S)-4-benzyl-3-(3-(3,5-difluorophenyl)propanoyl)oxazolidin-2-one

: 157634-02-1,132910-78-2
tert-butyl 2-formylpiperidine-1-carboxylate

: 877078-73-4
tert-butyl 2-((1S,2S)-2-(3,5-difluorobenzyl)-3-((s)-4-benzyl-2-oxooxazolidin-3-yl)-1-hydroxy-3-oxopropyl)piperidine-1-carboxylate

Guidance literature:: (S)-4-benzyl-3-(3-(3,5-difluorophenyl)propanoyl)oxazolidin-2-one; With di-n-butylboryl trifluoromethanesulfonate; triethylamine; In dichloromethane; at -78 - 0 ℃; for 0.333333h;

tert-butyl 2-formylpiperidine-1-carboxylate; In dichloromethane; at 20 ℃;

Reference yield:

: 877078-73-4
tert-butyl 2-((1S,2S)-2-(3,5-difluorobenzyl)-3-((s)-4-benzyl-2-oxooxazolidin-3-yl)-1-hydroxy-3-oxopropyl)piperidine-1-carboxylate

: 877078-74-5
(2S,3S)-2-(3,5-difluorobenzyl)-3-(1-(tert-butoxycarbonyl)piperidin-2-yl)-3-hydroxypropanoic acid

Guidance literature:: tert-butyl 2-((1S,2S)-2-(3,5-difluorobenzyl)-3-((s)-4-benzyl-2-oxooxazolidin-3-yl)-1-hydroxy-3-oxopropyl)piperidine-1-carboxylate; With lithium hydroxide; water; dihydrogen peroxide; In tetrahydrofuran; at 0 - 20 ℃;

With hydrogenchloride; In tetrahydrofuran;