877078-49-4

Basic information

• Product Name: 2-Oxazolidinone, 3-[3-(3,5-difluorophenyl)-1-oxopropyl]-4-(phenylmethyl)-, (4S)-
• CAS NO: 877078-49-4
• Molecular Formula: C19H17F2NO3
• Molecular Weight: 345.346
• Mol File: 877078-49-4.mol
• Article Data: 4

Chemical Properties

• CAS DataBase Reference: 2-Oxazolidinone, 3-[3-(3,5-difluorophenyl)-1-oxopropyl]-4-(phenylmethyl)-, (4S)-(CAS DataBase Reference)
• NIST Chemistry Reference: 2-Oxazolidinone, 3-[3-(3,5-difluorophenyl)-1-oxopropyl]-4-(phenylmethyl)-, (4S)-(877078-49-4)
• EPA Substance Registry System: 2-Oxazolidinone, 3-[3-(3,5-difluorophenyl)-1-oxopropyl]-4-(phenylmethyl)-, (4S)-(877078-49-4)

Safety Data

• Hazardous Substances Data: 877078-49-4(Hazardous Substances Data)

Upstream product

• 90719-32-7 (S)-4-Benzyl-2-oxazolidinone 
• 84315-24-2 3-(3,5-difluorophenyl)propionic acid 
• 95333-92-9 3-(3,5-difluorophenyl)propionyl chloride 

Downstream Products

• 1034606-46-6 (R)-tert-butyl 3-((1S,2S)-2-(3,5-difluorobenzyl)-3-((S)-4-benzyl-2-oxooxazolidin-3-yl)-1-hydroxy-3-oxopropyl)-3,4-dihydro-isoquinoline-2(1H)-carboxylate 
• 910447-70-0 tert-butyl 3-((1S,2S)-2-(3,5-difluorobenzyl)-3-((S)-4-benzyl-2-oxo-oxazolidin-3-yl)-1-hydroxy-3-oxopropyl)morpholine-4-carboxylate 
• 388072-23-9 (2R,3S)-3-amino-4-(3,5-difluorophenyl)-1-[(3-methoxybenzyl)amino]butan-2-ol 
• 388071-80-5 (1S,2R)-[1-(3,5-difluorobenzyl)-2-hydroxy-3-(3-methoxybenzylamino)propyl]-carbamic acid tert-butyl ester 
• 531521-48-9 (2S,3S)-3-amino-4-(3,5-difluorophenyl)butane-1,2-diol 
• 388071-27-0 tert-butyl (1S)-2-(3,5-difluorophenyl)-1-[(2S)-oxiranyl]ethylcarbamate 
• 531521-49-0 tert-butyl [(2S,3S)-1-(3,5-difluorophenyl)-3,4-dihydroxybutan-2-yl]carbamate 
• 877078-48-3 (2R,4R)-tert-butyl 2-((1S,2S)-2-(3,5-difluorobenzyl)-3-((S)-4-benzyl-2-oxooxazolidin-3-yl)-1-hydroxy-3-oxopropyl)-4-(allyloxy)pyrrolidine-1-carboxylate 

Relevant articles and documents

Highly stereoselective asymmetric aldol routes to tert-butyl-2-(3,5-difluorophenyl)-1-oxiran-2-yl)ethyl)carbamates: Building blocks for novel protease inhibitors

Enantioselective syntheses of tert-butyl ((S)-2-(3,5-difluorophenyl)-1-((S)-oxiran-2-yl)ethyl)carbamate and ((S)-2-(3,5-difluorophenyl)-1-((R)-oxiran-2-yl)ethyl)carbamate are described. We utilized asymmetric syn- and anti-aldol reactions to set both ster

Novel gamma-lactams as beta-secretase inhibitors

There is provided a series of novel substituted gamma-lactams of Formula (I) or a stereoisomer; or a pharmaceutically acceptable salt thereof, wherein R1, R2, R4, R5 and R6 as defined herein, their ph