N-(2-(6-Methoxy-2-phenylimidazo[1,2-a]pyridin-3-yl)ethyl)acetamide

Base Information

Chemical Name:N-(2-(6-Methoxy-2-phenylimidazo[1,2-a]pyridin-3-yl)ethyl)acetamide
CAS No.:877382-04-2
Molecular Formula:C18H19N3O2
Molecular Weight:309.368
Hs Code.:
ChEMBL ID:CHEMBL1823017
DSSTox Substance ID:DTXSID80470863
Pharos Ligand ID:N8VMGMUTKYQT

Synonyms:877382-04-2;CHEMBL1823017;N-(2-(6-Methoxy-2-phenylimidazo[1,2-a]pyridin-3-yl)ethyl)acetamide;N-[2-(6-methoxy-2-phenylimidazo[1,2-a]pyridin-3-yl)ethyl]acetamide;N-(2-{6-METHOXY-2-PHENYLIMIDAZO[1,2-A]PYRIDIN-3-YL}ETHYL)ACETAMIDE;CID 11702296;DTXSID80470863;BDBM50352005

Suppliers and Price of N-(2-(6-Methoxy-2-phenylimidazo[1,2-a]pyridin-3-yl)ethyl)acetamide

Supply Marketing:

Business phase:: The product has achieved commercial mass production^*data from LookChem market partment

Manufacturers and distributors:

Manufacture/Brand
Chemicals and raw materials
Packaging
price

Total 3 raw suppliers

Chemical Property of N-(2-(6-Methoxy-2-phenylimidazo[1,2-a]pyridin-3-yl)ethyl)acetamide

Chemical Property:

XLogP3:3
Hydrogen Bond Donor Count:1
Hydrogen Bond Acceptor Count:3
Rotatable Bond Count:5
Exact Mass:309.147726857
Heavy Atom Count:23
Complexity:398

Purity/Quality:: 99% ^*data from raw suppliers

Safty Information:

Pictogram(s):
Hazard Codes:

MSDS Files:: SDS file from LookChem

Useful:

Canonical SMILES:CC(=O)NCCC1=C(N=C2N1C=C(C=C2)OC)C3=CC=CC=C3

Technology Process of N-(2-(6-Methoxy-2-phenylimidazo[1,2-a]pyridin-3-yl)ethyl)acetamide

There total 7 articles about N-(2-(6-Methoxy-2-phenylimidazo[1,2-a]pyridin-3-yl)ethyl)acetamide which guide to synthetic route it. The literature collected by LookChem mainly comes from the sharing of users and the free literature resources found by Internet computing technology. We keep the original model of the professional version of literature to make it easier and faster for users to retrieve and use. At the same time, we analyze and calculate the most feasible synthesis route with the highest yield for your reference as below:

synthetic route:

Reference yield:

: 2-(6-methoxy-2-phenylimidazo[1,2-a]pyridin-3-yl)ethanamine

: 108-24-7
acetic anhydride

: 877382-04-2
N-(2-(6-methoxy-2-phenylimidazo[1,2-a]pyridin-3-yl)ethyl)acetamide

Guidance literature:: With pyridine; In dichloromethane; at 0 - 20 ℃; for 3h;
DOI:10.1016/j.ejmech.2011.06.030

Reference yield:

: 1335061-30-7
ethyl 2-(6-methoxy-2-phenylimidazolo[1,2-a]pyridin-3-yl)acetate

: 877382-04-2
N-(2-(6-methoxy-2-phenylimidazo[1,2-a]pyridin-3-yl)ethyl)acetamide

Guidance literature:: Multi-step reaction with 4 steps

1: sodium tetrahydroborate / tetrahydrofuran; ethanol / Reflux

2: tetrachloromethane; sodium azide; triphenylphosphine / N,N-dimethyl-formamide / 6 h / 90 °C

3: palladium 10% on activated carbon; hydrogen / methanol / 20 °C

4: pyridine / dichloromethane / 3 h / 0 - 20 °C

With pyridine; tetrachloromethane; sodium tetrahydroborate; sodium azide; palladium 10% on activated carbon; hydrogen; triphenylphosphine; In tetrahydrofuran; methanol; ethanol; dichloromethane; N,N-dimethyl-formamide;
DOI:10.1016/j.ejmech.2011.06.030

Reference yield:

: 877382-05-3
3-(6-methoxy-2-phenylimidazo[1,2-a]pyridin-3-yl)ethanol

: 877382-04-2
N-(2-(6-methoxy-2-phenylimidazo[1,2-a]pyridin-3-yl)ethyl)acetamide

Guidance literature:: Multi-step reaction with 3 steps

1: tetrachloromethane; sodium azide; triphenylphosphine / N,N-dimethyl-formamide / 6 h / 90 °C

2: palladium 10% on activated carbon; hydrogen / methanol / 20 °C

3: pyridine / dichloromethane / 3 h / 0 - 20 °C

With pyridine; tetrachloromethane; sodium azide; palladium 10% on activated carbon; hydrogen; triphenylphosphine; In methanol; dichloromethane; N,N-dimethyl-formamide;
DOI:10.1016/j.ejmech.2011.06.030