Urea, N-(3-chlorophenyl)-N'-[3-(phenylmethoxy)-2-pyridinyl]-

Base Information

Chemical Name:Urea, N-(3-chlorophenyl)-N'-[3-(phenylmethoxy)-2-pyridinyl]-
CAS No.:877459-37-5
Molecular Formula:C₁₉H₁₆ClN₃O₂
Molecular Weight:353.808
Hs Code.:
DSSTox Substance ID:DTXSID20399640
Nikkaji Number:J2.458.464J
Wikidata:Q82202306
Pharos Ligand ID:WRJFQ3J3W9DF
ChEMBL ID:CHEMBL199968
Mol file:877459-37-5.mol

Synonyms:1-(3-benzyloxypyridin-2-yl)-3-(3-chlorophenyl)urea;1-BzOP-3-ClPhU

Suppliers and Price of Urea, N-(3-chlorophenyl)-N'-[3-(phenylmethoxy)-2-pyridinyl]-

Supply Marketing:

Business phase:: The product has achieved commercial mass production^*data from LookChem market partment

Manufacturers and distributors:

Manufacture/Brand
Chemicals and raw materials
Packaging
price

Matrix Scientific
1-(3-Benzyloxypyridin-2-yl)-3-(3-chlorophenyl)urea
10mg
$ 146.00

Matrix Scientific
1-(3-Benzyloxypyridin-2-yl)-3-(3-chlorophenyl)urea
5mg
$ 105.00

Matrix Scientific
1-(3-Benzyloxypyridin-2-yl)-3-(3-chlorophenyl)urea
1mg
$ 90.00

American Custom Chemicals Corporation
1-(3-CHLOROPHENYL)-3-(3-(PHENYLMETHOXY)(2-PYRIDYL))UREA 95.00%
5MG
$ 499.10

Total 2 raw suppliers

Chemical Property of Urea, N-(3-chlorophenyl)-N'-[3-(phenylmethoxy)-2-pyridinyl]-

Chemical Property:

PSA：66.74000
LogP:5.04460
XLogP3:3.8
Hydrogen Bond Donor Count:2
Hydrogen Bond Acceptor Count:3
Rotatable Bond Count:5
Exact Mass:353.0931045
Heavy Atom Count:25
Complexity:418

Purity/Quality:

99% ^*data from raw suppliers

1-(3-Benzyloxypyridin-2-yl)-3-(3-chlorophenyl)urea ^*data from reagent suppliers

Safty Information:

Pictogram(s):
Hazard Codes:

MSDS Files:: SDS file from LookChem

Useful:

Canonical SMILES:C1=CC=C(C=C1)COC2=C(N=CC=C2)NC(=O)NC3=CC(=CC=C3)Cl

Technology Process of Urea, N-(3-chlorophenyl)-N'-[3-(phenylmethoxy)-2-pyridinyl]-

There total 2 articles about Urea, N-(3-chlorophenyl)-N'-[3-(phenylmethoxy)-2-pyridinyl]- which guide to synthetic route it. The literature collected by LookChem mainly comes from the sharing of users and the free literature resources found by Internet computing technology. We keep the original model of the professional version of literature to make it easier and faster for users to retrieve and use. At the same time, we analyze and calculate the most feasible synthesis route with the highest yield for your reference as below:

synthetic route:

Reference yield: 98.0%

: 2,2,2-trichloroethyl 3-(benzyloxy)pyridin-2-ylcarbamate

: 108-42-9
3-chloro-aniline

: 877459-37-5
1-(3-benzyloxy-pyridin-2-yl)-3-(3-chloro-phenyl)-urea

Guidance literature:: With zirconium(IV) tert-butoxide; In chlorobenzene; at 100 ℃; for 0.25h; microwave irradiation;
DOI:10.1021/ol0702728

Reference yield:

: 24016-03-3
2-amino-3-benzyloxypyridine

: 877459-37-5
1-(3-benzyloxy-pyridin-2-yl)-3-(3-chloro-phenyl)-urea

Guidance literature:: Multi-step reaction with 2 steps

1: 23 percent / pyridine / tetrahydrofuran / 0 - 20 °C

2: 98 percent / 4-methyl-2-hydroxyquinoline; Zr(Ot-Bu)4 / chlorobenzene / 0.25 h / 100 °C / microwave irradiation

With pyridine; zirconium(IV) tert-butoxide; In tetrahydrofuran; chlorobenzene;
DOI:10.1021/ol0702728