Estra-1,3,5(10)-triene-3,6,17-triol, triacetate, (6beta,17beta)-

Base Information

• Chemical Name: Estra-1,3,5(10)-triene-3,6,17-triol, triacetate, (6beta,17beta)-
• CAS No.: 6944-48-5
• Molecular Formula: C₂₄H₃₀O₆
• Molecular Weight: 414.499
• Mol file: 6944-48-5.mol

Synonyms:Estra-1,3,5(10)-triene-3,6b,17b-triol, triacetate (6CI,7CI,8CI); NSC 58791

Chemical Property of Estra-1,3,5(10)-triene-3,6,17-triol, triacetate, (6beta,17beta)-

Chemical Property:

• Vapor Pressure: 2.47E-10mmHg at 25°C
• Boiling Point: 505.3°C at 760 mmHg
• Flash Point: 217°C
• PSA: 78.90000
• Density: 1.22g/cm³
• LogP: 4.46140

Purity/Quality:

Safty Information:

• Pictogram(s):  
• Hazard Codes: 

MSDS Files:

SDS file from LookChem

Useful:

Technology Process of Estra-1,3,5(10)-triene-3,6,17-triol, triacetate, (6beta,17beta)-

There total 4 articles about Estra-1,3,5(10)-triene-3,6,17-triol, triacetate, (6beta,17beta)- which guide to synthetic route it. The literature collected by LookChem mainly comes from the sharing of users and the free literature resources found by Internet computing technology. We keep the original model of the professional version of literature to make it easier and faster for users to retrieve and use. At the same time, we analyze and calculate the most feasible synthesis route with the highest yield for your reference as below:

synthetic route:

Reference yield:

→ 3,6,17-Triacetat v. 6α-Hydroxyoestradiol (6626-42-2) + estratriene-(1,3,5(10))-triyl-(3,6β,17β)-triacetate (6944-48-5)

Guidance literature:

With aluminum isopropoxide; isopropyl alcohol; benzene; Behandeln des Reaktionsprodukts mit Acetanhydrid und Pyridin;

DOI:10.1021/ja01511a044

Reference yield:

6-oxo-3,17β-estradiol diacetate (3434-45-5) + aluminum isopropoxide (555-31-7) + isopropyl alcohol (67-63-0,8013-70-5) + benzene (71-43-2,26181-88-4,54682-86-9,13967-78-7,174973-66-1) → 3,6,17-Triacetat v. 6α-Hydroxyoestradiol (6626-42-2) + estratriene-(1,3,5(10))-triyl-(3,6β,17β)-triacetate (6944-48-5)

Guidance literature:

und Behandeln des Reaktionsprodukts mit Acetanhydrid und Pyridin;

DOI:10.1021/ja01511a044

Reference yield:

acetic anhydride (108-24-7) → estratriene-(1,3,5(10))-triyl-(3,6β,17β)-triacetate (6944-48-5)

Guidance literature:

With pyridine;

DOI:10.1021/ja01511a044

upstream raw materials:

6-oxo-3,17β-estradiol diacetate

aluminum isopropoxide

isopropyl alcohol

benzene