4-(3-Fluorophenylethynyl)-2-thiazolylamine

Base Information

Chemical Name:4-(3-Fluorophenylethynyl)-2-thiazolylamine
CAS No.:878018-65-6
Molecular Formula:C11H7FN2S
Molecular Weight:218.254
Hs Code.:
UNII:8KH9796NLC
ChEMBL ID:CHEMBL370559
Pharos Ligand ID:7BRH7JD2GTYW

Synonyms:8KH9796NLC;878018-65-6;UNII-8KH9796NLC;CHEMBL370559;CHEMBL-370559;2-Thiazolamine, 4-((3-fluorophenyl)ethynyl)-;4-(2-(3-Fluorophenyl)ethynyl)-2-thiazolamine;2-Thiazolamine, 4-(2-(3-fluorophenyl)ethynyl)-;4-(2-(3-Fluorophenyl)ethynyl)-1,3-thiazol-2-amine;4-(3-fluorophenylethynyl)-2-thiazolylamine;SCHEMBL4140841;BDBM50181770;PD181702

Suppliers and Price of 4-(3-Fluorophenylethynyl)-2-thiazolylamine

Supply Marketing:

Business phase:: The product has achieved commercial mass production^*data from LookChem market partment

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Chemical Property of 4-(3-Fluorophenylethynyl)-2-thiazolylamine

Chemical Property:

XLogP3:2.8
Hydrogen Bond Donor Count:1
Hydrogen Bond Acceptor Count:4
Rotatable Bond Count:2
Exact Mass:218.03139757
Heavy Atom Count:15
Complexity:283

Purity/Quality:

Safty Information:

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MSDS Files:

Useful:

Canonical SMILES:C1=CC(=CC(=C1)F)C#CC2=CSC(=N2)N

Technology Process of 4-(3-Fluorophenylethynyl)-2-thiazolylamine

There total 1 articles about 4-(3-Fluorophenylethynyl)-2-thiazolylamine which guide to synthetic route it. The literature collected by LookChem mainly comes from the sharing of users and the free literature resources found by Internet computing technology. We keep the original model of the professional version of literature to make it easier and faster for users to retrieve and use. At the same time, we analyze and calculate the most feasible synthesis route with the highest yield for your reference as below:

synthetic route:

Reference yield: 72.0%

: 329203-88-5
4-(trimethylsilylethynyl)-2-thiazolylamine

: 1121-86-4
1-Fluoro-3-iodobenzene

: 878018-65-6
4-(3-fluoro-phenylethynyl)-thiazol-2-ylamine

Guidance literature:: With copper(l) iodide; tetrakis(triphenylphosphine) palladium⁽⁰⁾; triethylamine; tetrabutyl ammonium fluoride; In tetrahydrofuran; N,N-dimethyl-formamide; at 85 ℃; for 0.25h;
DOI:10.1021/jm050570f