1,3-Dihydro-4-methyl-2H-1,5-benzodiazepin-2-one

Base Information

Chemical Name:1,3-Dihydro-4-methyl-2H-1,5-benzodiazepin-2-one
CAS No.:6276-48-8
Molecular Formula:C10H10 N2 O
Molecular Weight:174.202
Hs Code.:2933990090
European Community (EC) Number:228-473-0
NSC Number:36329
DSSTox Substance ID:DTXSID60211832
Nikkaji Number:J211.514J
Mol file:6276-48-8.mol

Synonyms:6276-48-8;1,3-Dihydro-4-methyl-2H-1,5-benzodiazepin-2-one;4-methyl-1,3-dihydro-1,5-benzodiazepin-2-one;4-Methyl-1,3-dihydro-2H-1,5-benzodiazepin-2-one;4-Methyl-1H-benzo[b][1,4]diazepin-2(3H)-one;4-methyl-2,3-dihydro-1H-1,5-benzodiazepin-2-one;NSC36329;4-Methyl-1,3-dihydro-benzo[b][1,4]diazepin-2-one;EINECS 228-473-0;2H-1,5-Benzodiazepin-2-one, 1,3-dihydro-4-methyl-;2,3-Dihydro-4-methyl-1H-1,5-benzodiazepin-2-one;Oprea1_221199;Oprea1_262593;SCHEMBL7507906;DTXSID60211832;MFCD00524790;NSC 36329;NSC-36329;STK300091;4-Methyl-1,5-benzo-diazepin-2-one;AKOS000310188;MS-2385;4-Methyl-1H-1,5-benzodiazepin-2(3H)-one;CS-0282461;4-Methyl-1H-1,5-benzodiazepine-2(3H)-one;SR-01000508395;SR-01000508395-1;4-Methyl-1,3-dihydro-2H-1,5-benzodiazepin-2-one #;Z56871569;4-Methyl-1,3-dihydro-2h-benzo[b][1,4]diazepin-2-one;F3161-0226

Suppliers and Price of 1,3-Dihydro-4-methyl-2H-1,5-benzodiazepin-2-one

Supply Marketing:

Business phase:: The product has achieved commercial mass production^*data from LookChem market partment

Manufacturers and distributors:

Manufacture/Brand
Chemicals and raw materials
Packaging
price

TRC
4-?Methyl-?2,?3-?dihydro-?1H-?1,?5-?benzodiazepin-?2-?one
5mg
$ 55.00

TRC
4-?Methyl-?2,?3-?dihydro-?1H-?1,?5-?benzodiazepin-?2-?one
1mg
$ 40.00

Crysdot
4-Methyl-1H-benzo[b][1,4]diazepin-2(3H)-one 97%
1g
$ 583.00

Total 10 raw suppliers

Chemical Property of 1,3-Dihydro-4-methyl-2H-1,5-benzodiazepin-2-one

Chemical Property:

Vapor Pressure:3.15E-05mmHg at 25°C
Boiling Point:355.3°C at 760 mmHg
Flash Point:168.7°C
PSA：41.46000
Density:1.22g/cm³
LogP:1.69480
XLogP3:0.8
Hydrogen Bond Donor Count:1
Hydrogen Bond Acceptor Count:2
Rotatable Bond Count:0
Exact Mass:174.079312947
Heavy Atom Count:13
Complexity:247

Purity/Quality:: 4-?Methyl-?2,?3-?dihydro-?1H-?1,?5-?benzodiazepin-?2-?one ^*data from reagent suppliers

Safty Information:

Pictogram(s):
Hazard Codes:

MSDS Files:: SDS file from LookChem

Useful:

Canonical SMILES:CC1=NC2=CC=CC=C2NC(=O)C1
Uses 4-?Methyl-?2,?3-?dihydro-?1H-?1,?5-?benzodiazepin-?2-?one is used in the preparation of benzodiazepine pharmacophores, including s-triazine derivatives which display medicinal interest. Also an impurity of Filbanserin (F336750), an agonist of serotonin-5HT1A receptor and an antagonist of the 5-HT2A receptor. Binds dopamine receptors with Ki values ranging from 4-24 nM. Used to treat hypoactive sexual desire disorder in females.

Technology Process of 1,3-Dihydro-4-methyl-2H-1,5-benzodiazepin-2-one

There total 21 articles about 1,3-Dihydro-4-methyl-2H-1,5-benzodiazepin-2-one which guide to synthetic route it. The literature collected by LookChem mainly comes from the sharing of users and the free literature resources found by Internet computing technology. We keep the original model of the professional version of literature to make it easier and faster for users to retrieve and use. At the same time, we analyze and calculate the most feasible synthesis route with the highest yield for your reference as below:

synthetic route:

Reference yield: 98.0%