2-(Dichloromethyl)-5-fluoroimidazo[1,2-a]pyridine

Base Information

Chemical Name:2-(Dichloromethyl)-5-fluoroimidazo[1,2-a]pyridine
CAS No.:878197-91-2
Molecular Formula:C8H5Cl2FN2
Molecular Weight:219.04300
Hs Code.:
DSSTox Substance ID:DTXSID00704455
Wikidata:Q82636884
Mol file:878197-91-2.mol

Synonyms:2-(Dichloromethyl)-5-fluoroimidazo[1,2-a]pyridine;878197-91-2;SCHEMBL3735301;DTXSID00704455;YCOFITAQIPULIF-UHFFFAOYSA-N;FT-0718778;imidazo[1,2-a]pyridine,2-(dichloromethyl)-5-fluoro-

Suppliers and Price of 2-(Dichloromethyl)-5-fluoroimidazo[1,2-a]pyridine

Supply Marketing:

Business phase:: The product has achieved commercial mass production^*data from LookChem market partment

Manufacturers and distributors:

Manufacture/Brand
Chemicals and raw materials
Packaging
price

American Custom Chemicals Corporation
2-(DICHLOROMETHYL)-5-FLUOROIMIDAZO[1,2-A]PYRIDINE 95.00%
5MG
$ 498.84

AccelPharmtech
2-(dichloromethyl)-5-fluoro-Imidazo[1,2-a]pyridine 97.00%
25G
$ 5520.00

AccelPharmtech
2-(dichloromethyl)-5-fluoro-Imidazo[1,2-a]pyridine 97.00%
5G
$ 2960.00

Total 4 raw suppliers

Chemical Property of 2-(Dichloromethyl)-5-fluoroimidazo[1,2-a]pyridine

Chemical Property:

PSA：17.30000
LogP:2.94960
XLogP3:3.3
Hydrogen Bond Donor Count:0
Hydrogen Bond Acceptor Count:2
Rotatable Bond Count:1
Exact Mass:217.9813817
Heavy Atom Count:13
Complexity:191

Purity/Quality:

98% ^*data from raw suppliers

2-(DICHLOROMETHYL)-5-FLUOROIMIDAZO[1,2-A]PYRIDINE 95.00% ^*data from reagent suppliers

Safty Information:

Pictogram(s):
Hazard Codes:

MSDS Files:

Useful:

Canonical SMILES:C1=CC2=NC(=CN2C(=C1)F)C(Cl)Cl

Technology Process of 2-(Dichloromethyl)-5-fluoroimidazo[1,2-a]pyridine

There total 3 articles about 2-(Dichloromethyl)-5-fluoroimidazo[1,2-a]pyridine which guide to synthetic route it. The literature collected by LookChem mainly comes from the sharing of users and the free literature resources found by Internet computing technology. We keep the original model of the professional version of literature to make it easier and faster for users to retrieve and use. At the same time, we analyze and calculate the most feasible synthesis route with the highest yield for your reference as below:

synthetic route:

Reference yield: 65.0%

: 918-00-3,861255-82-5
1,1,1-trichloroacetone

: 1597-32-6
6-fluoro-pyridin-2-ylamine

: 878197-91-2
2-(dichloromethyl)-5-fluoroimidazo[1,2-a]pyridine

Guidance literature:: In diethylene glycol dimethyl ether; at 85 ℃; for 15h;

Reference yield: 65.0%

: 921-03-9
1,1,3-trichloroacetone

: 1597-32-6
6-fluoro-pyridin-2-ylamine

: 878197-91-2
2-(dichloromethyl)-5-fluoroimidazo[1,2-a]pyridine

Guidance literature:: In 1,2-dimethoxyethane; at 85 ℃; for 15h;

Reference yield:

: C₈H₈Cl₂FN₂O⁽¹⁺⁾*Cl^(1-)

: 878197-91-2
2-(dichloromethyl)-5-fluoroimidazo[1,2-a]pyridine

Guidance literature:: C₈H₈Cl₂FN₂O⁽¹⁺⁾*Cl^(1-); In ethanol; for 4h; Heating / reflux;

With sodium hydrogencarbonate; In dichloromethane; water; Product distribution / selectivity;