6-[2-(2,4-Dichlorophenyl)ethyl]-4-hydroxyoxan-2-one

Base Information

Chemical Name:6-[2-(2,4-Dichlorophenyl)ethyl]-4-hydroxyoxan-2-one
CAS No.:90761-31-2
Molecular Formula:C13H14 Cl2 O3
Molecular Weight:289.15
Hs Code.:
DSSTox Substance ID:DTXSID30920186
Mol file:90761-31-2.mol

Synonyms:7-(2,4-dichlorophenyl)-3-hydroxy-5-heptanolide;DCPHH

Suppliers and Price of 6-[2-(2,4-Dichlorophenyl)ethyl]-4-hydroxyoxan-2-one

Supply Marketing:

Business phase:: The product has achieved commercial mass production^*data from LookChem market partment

Manufacturers and distributors:

Manufacture/Brand
Chemicals and raw materials
Packaging
price

Total 3 raw suppliers

Chemical Property of 6-[2-(2,4-Dichlorophenyl)ethyl]-4-hydroxyoxan-2-one

Chemical Property:

Vapor Pressure:2.98E-09mmHg at 25°C
Boiling Point:459.8°Cat760mmHg
Flash Point:231.9°C
PSA：46.53000
Density:1.356g/cm³
LogP:2.99250
XLogP3:3.2
Hydrogen Bond Donor Count:1
Hydrogen Bond Acceptor Count:3
Rotatable Bond Count:3
Exact Mass:288.0319997
Heavy Atom Count:18
Complexity:298

Purity/Quality:

Safty Information:

Pictogram(s):
Hazard Codes:

MSDS Files:: SDS file from LookChem

Useful:

Canonical SMILES:C1C(CC(=O)OC1CCC2=C(C=C(C=C2)Cl)Cl)O

Technology Process of 6-[2-(2,4-Dichlorophenyl)ethyl]-4-hydroxyoxan-2-one

There total 28 articles about 6-[2-(2,4-Dichlorophenyl)ethyl]-4-hydroxyoxan-2-one which guide to synthetic route it. The literature collected by LookChem mainly comes from the sharing of users and the free literature resources found by Internet computing technology. We keep the original model of the professional version of literature to make it easier and faster for users to retrieve and use. At the same time, we analyze and calculate the most feasible synthesis route with the highest yield for your reference as below:

synthetic route:

Reference yield: 79.0%

: 96720-15-9
6(R)-[2-(2,4-dichlorophenyl)ethyl]-4(R)-(methoxymethoxy)tetrahydro-2H-pyran-2-one

: 90761-31-2
7-(2,4-Dichlorophenyl)-D-erythro-3-hydroxy-5-heptanolide

Guidance literature:: With dimethylboron bromide; at -78 ℃; for 1h;
DOI:10.1016/S0040-4039(00)98429-6

Reference yield:

: 6(S)-[2-(2,4-dichlorophenyl)ethyl]-2-hydroxy-4(R)-hydroxy-3,4,5,6-tetrahydro-2H-pyran

: 311-28-4
tetra-(n-butyl)ammonium iodide

: (4R,6S) 6-[2-(2,4-dichlorophenylethyl]-4-hydroxy-3,4,5,6-tetrahydro-2H-pyran-2-one

: 78444-25-4,78444-26-5,86097-55-4,86097-56-5,90761-31-2,129830-09-7
6-[2-(2,4-dichlorophenyl)ethyl]-4-hydroxy-3,4,5,6-tetrahydro-2H-pyran-2-on

Guidance literature:: With N-iodo-succinimide; sodium thiosulfate; In dichloromethane;

Reference yield:

: 4613-68-7,14260-67-4,22248-90-4,74996-06-8
O¹,O²-isopropylidene-α-D-erythro-3-deoxy-pentodiald-1,4-ose

: 90761-31-2
7-(2,4-Dichlorophenyl)-D-erythro-3-hydroxy-5-heptanolide

Guidance literature:: Multi-step reaction with 6 steps

1: 1.) t-BuOK / 2.) THF, DMF, 0 to room temp.

2: hydrogen / 10percent Pd/C / ethyl acetate / 760 Torr

3: p-TsOH / acetonitrile; H₂O / 3 h / 90 °C

4: 1.) NaH / 2.) DMF, DMSO, 0 to room temp.

5: HgCl₂, HgO / acetonitrile; H₂O / 65 °C

6: N-Iodosuccinimide, (n-Bu)4N⁽¹⁺⁾*l^(1-) / CH₂Cl₂ / Ambient temperature

With N-iodo-succinimide; potassium tert-butylate; hydrogen; tetra-(n-butyl)ammonium iodide; sodium hydride; toluene-4-sulfonic acid; mercury dichloride; mercury(II) oxide; palladium on activated charcoal; In dichloromethane; water; ethyl acetate; acetonitrile;
DOI:10.1016/S0040-4039(01)80835-2