[(3S)-oxolan-3-yl] N-[(2S,3R)-4-[cyclopentylmethyl-(4-methoxyphenyl)su lfonyl-amino]-3-hydroxy-1-phenyl-butan-2-yl]carbamate

Base Information

• Chemical Name: [(3S)-oxolan-3-yl] N-[(2S,3R)-4-[cyclopentylmethyl-(4-methoxyphenyl)su lfonyl-amino]-3-hydroxy-1-phenyl-butan-2-yl]carbamate
• CAS No.: 160231-42-5
• Molecular Formula: C₂₈H₃₈N₂O₇S
• Molecular Weight: 546.685
• Mol file: 160231-42-5.mol

Synonyms:Carbamicacid,[(1S,2R)-3-[(cyclopentylmethyl)[(4-methoxyphenyl)sulfonyl]amino]-2-hydroxy-1-(phenylmethyl)propyl]-,(3S)-tetrahydro-3-furanyl ester (9CI); Carbamic acid,[3-[(cyclopentylmethyl)[(4-methoxyphenyl)sulfonyl]amino]-2-hydroxy-1-(phenylmethyl)propyl]-,tetrahydro-3-furanyl ester, [3S-[3R*(1R*,2S*)]]-; VB 11328

Chemical Property of [(3S)-oxolan-3-yl] N-[(2S,3R)-4-[cyclopentylmethyl-(4-methoxyphenyl)su lfonyl-amino]-3-hydroxy-1-phenyl-butan-2-yl]carbamate

Chemical Property:

• PSA: 126.27000
• Density: 1.3g/cm³
• LogP: 4.64860

Purity/Quality:

Safty Information:

• Pictogram(s):  
• Hazard Codes: 

MSDS Files:

SDS file from LookChem

Useful:

Technology Process of [(3S)-oxolan-3-yl] N-[(2S,3R)-4-[cyclopentylmethyl-(4-methoxyphenyl)su lfonyl-amino]-3-hydroxy-1-phenyl-butan-2-yl]carbamate

There total 2 articles about [(3S)-oxolan-3-yl] N-[(2S,3R)-4-[cyclopentylmethyl-(4-methoxyphenyl)su lfonyl-amino]-3-hydroxy-1-phenyl-butan-2-yl]carbamate which guide to synthetic route it. The literature collected by LookChem mainly comes from the sharing of users and the free literature resources found by Internet computing technology. We keep the original model of the professional version of literature to make it easier and faster for users to retrieve and use. At the same time, we analyze and calculate the most feasible synthesis route with the highest yield for your reference as below:

synthetic route:

Reference yield:

C21H32N2O4 (160232-71-3) + 4-methoxy-phenyl-sulphonyl chloride (98-68-0) → N-Cyclopentylmethyl-N-((2 syn, 3S)-2-hydroxy-4-phenyl-3-((S)-tetrahydrofuran-3-yloxycarbonylamino)-butyl)-4-methoxy-benzenesulfonamide (160231-42-5)

Guidance literature:

With sodium hydrogencarbonate; In dichloromethane; water; at 20 ℃; for 4h;

Reference yield:

→ N-Cyclopentylmethyl-N-((2 syn, 3S)-2-hydroxy-4-phenyl-3-((S)-tetrahydrofuran-3-yloxycarbonylamino)-butyl)-4-methoxy-benzenesulfonamide (160231-42-5)

Guidance literature:

upstream raw materials:

C₂₁H₃₂N₂O₄

4-methoxy-phenyl-sulphonyl chloride

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