N-(5,5-DIMETHYL-2-OXOTETRAHYDRO-3-FURYL)-2,2,2-TRIFLUOROACETAMIDE

Base Information

Chemical Name:N-(5,5-DIMETHYL-2-OXOTETRAHYDRO-3-FURYL)-2,2,2-TRIFLUOROACETAMIDE
CAS No.:77694-20-3
Molecular Formula:C₈H₁₀F₃NO₃
Molecular Weight:225.168
Hs Code.:2932209090
Mol file:77694-20-3.mol

Synonyms:N-(5,5-DIMETHYL-2-OXOTETRAHYDRO-3-FURYL)-2,2,2-TRIFLUOROACETAMIDE

Suppliers and Price of N-(5,5-DIMETHYL-2-OXOTETRAHYDRO-3-FURYL)-2,2,2-TRIFLUOROACETAMIDE

Supply Marketing:

Business phase:: The product has achieved commercial mass production^*data from LookChem market partment

Manufacturers and distributors:

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Total 1 raw suppliers

Chemical Property of N-(5,5-DIMETHYL-2-OXOTETRAHYDRO-3-FURYL)-2,2,2-TRIFLUOROACETAMIDE

Chemical Property:

Vapor Pressure:0.000164mmHg at 25°C
Melting Point:115 °C
Boiling Point:330.7°C at 760 mmHg
Flash Point:153.8°C
PSA：55.40000
Density:1.34g/cm³
LogP:1.14990

Purity/Quality:: 98% ^*data from raw suppliers

Safty Information:

Pictogram(s):
Hazard Codes:

MSDS Files:: SDS file from LookChem

Useful:

Technology Process of N-(5,5-DIMETHYL-2-OXOTETRAHYDRO-3-FURYL)-2,2,2-TRIFLUOROACETAMIDE

There total 6 articles about N-(5,5-DIMETHYL-2-OXOTETRAHYDRO-3-FURYL)-2,2,2-TRIFLUOROACETAMIDE which guide to synthetic route it. The literature collected by LookChem mainly comes from the sharing of users and the free literature resources found by Internet computing technology. We keep the original model of the professional version of literature to make it easier and faster for users to retrieve and use. At the same time, we analyze and calculate the most feasible synthesis route with the highest yield for your reference as below:

synthetic route:

Reference yield: 100.0%

: 77443-36-8,77694-20-3
L-γ-Methyl-α-trifluoracetylamino-γ-valeriansaeurelacton

: 77694-20-3
4,4-dimethyl-2-(2,2,2-trifluoroacetamido)butyrolactone

Guidance literature:: With sodium hydroxide; In tetrahydrofuran; for 2h;

Reference yield: 94.0%

: 15722-67-5,42417-45-8,65451-72-1
L-γ-Leucinlacton-hydrochlorid

: 407-25-0
trifluoroacetic anhydride

: 77443-36-8,77694-20-3
L-γ-Methyl-α-trifluoracetylamino-γ-valeriansaeurelacton

Guidance literature:: With triethylamine; In chloroform; for 1h; Ambient temperature;

Reference yield: 60.0%

: 1344703-21-4
tert-butyl 4-oxo-2-(2,2,2-trifluoroacetamido)pentanoate

: 75-24-1
trimethylaluminum

: 77694-20-3
4,4-dimethyl-2-(2,2,2-trifluoroacetamido)butyrolactone

Guidance literature:: tert-butyl 4-oxo-2-(2,2,2-trifluoroacetamido)pentanoate; With zinc(II) chloride; In tetrahydrofuran; at 20 ℃; for 0.5h; Inert atmosphere;

trimethylaluminum; In tetrahydrofuran; toluene; at 0 - 20 ℃; for 3h; Inert atmosphere;
DOI:10.1055/s-0030-1260136