Benzyl 2-acetamido-6-O-(2-acetamido-2,4-dideoxy-4-fluoroglucopyranosyl)-2-deoxygalactopyranoside

Base Information

Chemical Name:Benzyl 2-acetamido-6-O-(2-acetamido-2,4-dideoxy-4-fluoroglucopyranosyl)-2-deoxygalactopyranoside
CAS No.:115973-78-9
Molecular Formula:C23H33 F N2 O10
Molecular Weight:516.51
Hs Code.:
DSSTox Substance ID:DTXSID00921882
Wikidata:Q82895028
Mol file:115973-78-9.mol

Synonyms:BAADFGG;benzyl 2-acetamido-6-O-(2-acetamido-2,4-dideoxy-4-fluoroglucopyranosyl)-2-deoxygalactopyranoside

Suppliers and Price of Benzyl 2-acetamido-6-O-(2-acetamido-2,4-dideoxy-4-fluoroglucopyranosyl)-2-deoxygalactopyranoside

Supply Marketing:

Business phase:: The product has achieved commercial mass production^*data from LookChem market partment

Manufacturers and distributors:

Manufacture/Brand
Chemicals and raw materials
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price

Total 1 raw suppliers

Chemical Property of Benzyl 2-acetamido-6-O-(2-acetamido-2,4-dideoxy-4-fluoroglucopyranosyl)-2-deoxygalactopyranoside

Chemical Property:

Vapor Pressure:7.41E-32mmHg at 25°C
Boiling Point:864.1°Cat760mmHg
Flash Point:476.4°C
PSA：183.02000
Density:1.42g/cm³
LogP:-0.22730
XLogP3:-2.2
Hydrogen Bond Donor Count:6
Hydrogen Bond Acceptor Count:11
Rotatable Bond Count:9
Exact Mass:516.21192342
Heavy Atom Count:36
Complexity:727

Purity/Quality:: 95% ^*data from raw suppliers

Safty Information:

Pictogram(s):
Hazard Codes:

MSDS Files:: SDS file from LookChem

Useful:

Canonical SMILES:CC(=O)NC1C(C(C(OC1OCC2=CC=CC=C2)COC3C(C(C(C(O3)CO)F)O)NC(=O)C)O)O
Isomeric SMILES:CC(=O)N[C@@H]1[C@H]([C@H]([C@H](O[C@H]1OCC2=CC=CC=C2)CO[C@H]3[C@@H]([C@H]([C@@H]([C@H](O3)CO)F)O)NC(=O)C)O)O

Technology Process of Benzyl 2-acetamido-6-O-(2-acetamido-2,4-dideoxy-4-fluoroglucopyranosyl)-2-deoxygalactopyranoside

There total 8 articles about Benzyl 2-acetamido-6-O-(2-acetamido-2,4-dideoxy-4-fluoroglucopyranosyl)-2-deoxygalactopyranoside which guide to synthetic route it. The literature collected by LookChem mainly comes from the sharing of users and the free literature resources found by Internet computing technology. We keep the original model of the professional version of literature to make it easier and faster for users to retrieve and use. At the same time, we analyze and calculate the most feasible synthesis route with the highest yield for your reference as below:

synthetic route:

Reference yield: 95.0%

: 1193357-28-6
C₃₁H₄₁FN₂O₁₄

: 115973-78-9
benzyl 6-O-[2-acetamido-2,4-dideoxy-4-fluoro-β-D-glucopyranosyl]-2-acetamido-2-deoxy-α-D-galactopyranoside

Guidance literature:: With methanol; sodium methylate; at 45 ℃; for 12h;
DOI:10.1016/j.tet.2009.07.089

Reference yield: 87.0%

: 115973-77-8
benzyl 2-acetamido-6-O-(2-acetamido-3,6-di-O-acetyl-2,4-dideoxy-4-fluoro-β-D-glucopyranosyl)-3-O-acetyl-2-deoxy-α-D-galactopyranoside

: 115973-78-9
benzyl 6-O-[2-acetamido-2,4-dideoxy-4-fluoro-β-D-glucopyranosyl]-2-acetamido-2-deoxy-α-D-galactopyranoside

Guidance literature:: With sodium methylate; In methanol; for 24h; Ambient temperature;
DOI:10.1016/0008-6215(88)80166-6

Reference yield:

: 75869-83-9
benzyl 2-acetamido-3,6-di-O-benzyl-2-deoxy-α-D-galactopyranoside

: 115973-78-9
benzyl 6-O-[2-acetamido-2,4-dideoxy-4-fluoro-β-D-glucopyranosyl]-2-acetamido-2-deoxy-α-D-galactopyranoside

Guidance literature:: Multi-step reaction with 6 steps

1: 55 percent / diethylaminosulfur trifluoride / bis-(2-methoxy-ethyl) ether / 1 h / Ambient temperature

2: H₂ / 10percent Pd-C / acetic acid / 48 h / 2587.7 Torr / Ambient temperature

3: pyridine / 24 h / Ambient temperature

4: 69 percent / trimethylsilyl trifluoromethanesulfonate / 1,2-dichloro-ethane / 24 h / 50 °C

5: 61 percent / p-toluenesulfonic acid / 1,2-dichloro-ethane / 24 h / 75 °C

6: 87 percent / sodium methoxide / methanol / 24 h / Ambient temperature

With diethylamino-sulfur trifluoride; trimethylsilyl trifluoromethanesulfonate; hydrogen; sodium methylate; toluene-4-sulfonic acid; palladium on activated charcoal; In pyridine; methanol; diethylene glycol dimethyl ether; acetic acid; 1,2-dichloro-ethane;
DOI:10.1016/0008-6215(88)80166-6