N-(1,2-Diphenylethyl)nicotinamide

Base Information

• Chemical Name: N-(1,2-Diphenylethyl)nicotinamide
• CAS No.: 553-06-0
• Molecular Formula: C20H18 N2 O
• Molecular Weight: 302.376
• Hs Code.: 2933399090
• European Community (EC) Number: 209-031-6
• UNII: 9882JU353F
• DSSTox Substance ID: DTXSID80870607
• Nikkaji Number: J188.403D
• Wikidata: Q3876099
• Metabolomics Workbench ID: 154329
• ChEMBL ID: CHEMBL3707234
• Mol file: 553-06-0.mol

Synonyms:Nicofetamide;N-(1,2-Diphenylethyl)nicotinamide;553-06-0;lispamina;lyspamin;N-(1,2-diphenylethyl)pyridine-3-carboxamide;EINECS 209-031-6;nicofetamida;UNII-9882JU353F;9882JU353F;N-(1,2-Diphenylethyl)-3-pyridinecarboxamide;C 1065;C-1065;NICOFETAMIDE [MI];NICOFETAMIDE [MART.];NICOFETAMIDE [WHO-DD];SCHEMBL254029;CHEMBL3707234;CHEBI:81301;DTXSID80870607;DWODOIKZDGJOPQ-UHFFFAOYSA-N;AKOS017117289;DB13531;1-NICOTINYLAMINO-1,2-DIPHENYLETHANE;NICOTINAMIDE, N-(1,2-DIPHENYLETHYL)-;C17729;3-Pyridinecarboxamide, N-(1,2-diphenylethyl)-;Q3876099;Z73400342

Chemical Property of N-(1,2-Diphenylethyl)nicotinamide

Chemical Property:

• Vapor Pressure: 3.08E-11mmHg at 25°C
• Melting Point: 159°
• Boiling Point: 528°Cat760mmHg
• Flash Point: 273.1°C
• PSA: 45.48000
• Density: 1.155g/cm³
• LogP: 4.37020
• XLogP3: 3.6
• Hydrogen Bond Donor Count: 1
• Hydrogen Bond Acceptor Count: 2
• Rotatable Bond Count: 5
• Exact Mass: 302.141913202
• Heavy Atom Count: 23
• Complexity: 359

Purity/Quality:

99% ^*data from raw suppliers

NICOFETAMIDE 95.00% ^*data from reagent suppliers

Safty Information:

• Pictogram(s):  
• Hazard Codes: 

MSDS Files:

SDS file from LookChem

Useful:

• Canonical SMILES: C1=CC=C(C=C1)CC(C2=CC=CC=C2)NC(=O)C3=CN=CC=C3

Technology Process of N-(1,2-Diphenylethyl)nicotinamide

There total 2 articles about N-(1,2-Diphenylethyl)nicotinamide which guide to synthetic route it. The literature collected by LookChem mainly comes from the sharing of users and the free literature resources found by Internet computing technology. We keep the original model of the professional version of literature to make it easier and faster for users to retrieve and use. At the same time, we analyze and calculate the most feasible synthesis route with the highest yield for your reference as below:

synthetic route:

Reference yield:

nicotinic acid (59-67-6) + (R,S)-1,2-diphenylethylamine (25611-78-3) → N-(1,2-diphenyl-ethyl)-nicotinamide (553-06-0)

Guidance literature:

With Isopropylbenzene; Entfernen des entstehenden H₂O;

Reference yield:

(R,S)-1,2-diphenylethylamine (25611-78-3) + pyridine-3-carbonyl chloride hydrochloride (20260-53-1) → N-(1,2-diphenyl-ethyl)-nicotinamide (553-06-0)

Guidance literature:

With pyridine;

upstream raw materials:

nicotinic acid

(R,S)-1,2-diphenylethylamine

pyridine-3-carbonyl chloride hydrochloride