Olivacine

Base Information

Chemical Name:Olivacine
CAS No.:484-49-1
Molecular Formula:C₁₇H₁₄N₂
Molecular Weight:246.312
Hs Code.:
NSC Number:70134
UNII:5WSL5LL2C3
DSSTox Substance ID:DTXSID10197511
Nikkaji Number:J12.520B
Wikipedia:Olivacine
Wikidata:Q15425302,Q104250908
Metabolomics Workbench ID:70230
ChEMBL ID:CHEMBL306472
Mol file:484-49-1.mol

Synonyms:olivacine;olivacine oxalate (1:1)

Suppliers and Price of Olivacine

Supply Marketing:

Business phase:: The product has achieved commercial mass production^*data from LookChem market partment

Manufacturers and distributors:

Manufacture/Brand
Chemicals and raw materials
Packaging
price

American Custom Chemicals Corporation
1,5-DIMETHYL-6H-PYRIDO[4,3-B]CARBAZOLE 98.00%
25MG
$ 1372.14

AHH
1,5-Dimethyl-6H-pyrido[4,3-b]carbazole 99%
1000g
$ 495.00

Total 5 raw suppliers

Chemical Property of Olivacine

Chemical Property:

Vapor Pressure:2.04E-09mmHg at 25°C
Melting Point:317-325°
Boiling Point:493.9°Cat760mmHg
Flash Point:226.3°C
PSA：25.25000
Density:1.257g/cm³
LogP:1.91490
XLogP3:3.8
Hydrogen Bond Donor Count:1
Hydrogen Bond Acceptor Count:2
Rotatable Bond Count:0
Exact Mass:246.115698455
Heavy Atom Count:19
Complexity:599

Purity/Quality:

99% ^*data from raw suppliers

1,5-DIMETHYL-6H-PYRIDO[4,3-B]CARBAZOLE 98.00% ^*data from reagent suppliers

Safty Information:

Pictogram(s):
Hazard Codes:

MSDS Files:: SDS file from LookChem

Useful:

Canonical SMILES:CC1=C2C=CNC(=C2C=C3C1=NC4=CC=CC=C43)C
Description This alkaloid has recently been shown to exhibit a marked antineoplastic activity. Administration of 25 or 50 mg/kg intraperitoneally on alternate days or daily until death to mice which had been inoculated with a single intraperitoneal dose of 106 -102 LI2l0 leukemia cells increased the survival time by 89-229 per cent compared with control animals.Japanese workers have recently reported the synthesis of olivacine by heating indole with 4(1-hydroxyethyl)-3-methoxymethyl-2-methylpyridine in 47 per cent HBr.

Technology Process of Olivacine

There total 82 articles about Olivacine which guide to synthetic route it. The literature collected by LookChem mainly comes from the sharing of users and the free literature resources found by Internet computing technology. We keep the original model of the professional version of literature to make it easier and faster for users to retrieve and use. At the same time, we analyze and calculate the most feasible synthesis route with the highest yield for your reference as below:

synthetic route:

Reference yield: 85.0%

: 121624-62-2
1,2-dihydro-1,5-dimethyl-2-(4-toluenesulphonyl)-6H-pyrido<4,3-b>carbazole

: 484-49-1
Guatambuinine

Guidance literature:: With ammonia; sodium; In ammonia;
DOI:10.1016/S0040-4039(00)82385-0

Reference yield: 82.0%

: 4241-44-5
3,14-dihydroolivacine

: 484-49-1
Guatambuinine

Guidance literature:: palladium on activated charcoal; In decalin; for 1.5h; Heating;
DOI:10.1021/jo00302a013

Reference yield: 71.0%

: N-(2-chlorophenyl)-1,5-dimethylisoquinolin-6-amine

: 484-49-1
Guatambuinine

: 4,11b-dimethyl-11bH-pyrido[3,4-c]carbazole

Guidance literature:: With palladium diacetate; potassium carbonate; tri tert-butylphosphoniumtetrafluoroborate; In N,N-dimethyl-formamide; at 140 ℃; for 0.5h; Reagent/catalyst; Temperature; Solvent; Inert atmosphere;
DOI:10.3390/molecules23061402