4241-44-5

Usage

Chemical class

Carbazoles Aromatic compounds commonly found in nature and used in various industrial applications.

Molecular structure

Complex Characterized by two methyl groups and a dihydro pyrido ring.

Chemical and physical properties

Unique The presence of methyl groups and the dihydro pyrido ring contribute to its distinct properties.

Biological activities

Potential The compound is being studied for its possible biological activities.

Applications

Pharmaceutical and agrochemical industries Due to its potential biological activities, it is being investigated for use in these sectors.

Handling and study

Careful The compound's complex structure and potential reactivity necessitate cautious handling and in-depth research to fully understand and utilize its properties.

Upstream product

• 37687-32-4 5,11-dimethyl-4,6-dihydro-3H-pyrido[4,3-b]carbazole 
• 61253-30-3 N-acetyl-2-(1-methyl-9H-carbazol-2-yl)ethylamine 
• 100880-19-1 2-(1-methyl-9H-carbazol-2-yl)acetonitrile 
• 93009-07-5 ethyl 2-(1-oxo-2,3,4,9-tetrahydro-1H-carbazol-2-yl)-acetate 
• 92199-96-7 2-(1-oxo-2,3,4,9-tetrahydro-1H-carbazol-2-yl)acetic acid 
• 5531-70-4 2-(1-methyl-9H-carbazol-2-yl)ethan-1-amine 
• 127472-68-8 r-2-(cyanomethyl)-1,2,3,4,t-4a,t-9a-hexahydro-c-1-methyl-t-3-(phenylsulfonyl)carbazole 
• 127472-69-9 r-2-(cyanomethyl)-1,2,3,4,t-4a,t-9a-hexahydro-c-1-methylcarbazole 
• 127472-67-7 r-1-methyl-3-(phenylsulfonyl)-1,4,t-4a,t-9a-tetrahydrocarbazole 

Downstream Products

• 484-49-1 Guatambuinine 

Relevant academic research and scientific papers

Total Synthesis of Olivacine and Ellipticine via a Lactone Ring-Opening and Aromatization Cascade

Effective preparation of olivacine and ellipticine via late-stage D-ring cyclization is described. Key features of the synthetic routes include trifluoroacetic acid-mediated formation of a lactone that is fused to a tetrahydrocarbazole derivative and its one-pot two-step ring opening and aromatization mediated by para-toluenesulfonic acid and palladium on carbon, respectively.

Concise Total Syntheses of Pyrido[4,3-b]carbazole Alkaloids Using Copper-Mediated 6π-Electrocyclization

Concise syntheses of 9-methoxyellipticine, 3,4-dihydroellipticine (μ-alkaloid D), 1,2,3,4-tetrahydroellipticine, 2-methyl-1,2,3,4-tetrahydroellipticine, olivacine, 3,4-dihydroolivacine, (±)-guatambuine, and (±)-janetine were developed starting from hexatriene intermediates readily obtained by Pd-catalyzed tandem cyclization/cross-coupling reaction of indolylborates. The route enables the facile construction of pyrido[4,3-b]carbazoles by Cu-catalyzed 6π-electrocyclization and subsequent transformation of the pyridocarbazole intermediates into pyrido[4,3-b]carbazole alkaloids. Concise total syntheses of pyrido[4,3-b]carbazole alkaloids were accomplished using Cu-catalyzed 6π-electrocyclization of hexatriene as a key step.

New Synthesis of the 6H-Pyridocarbazoles Ellipticine and Olivacine via Cycloaddition of 2-Phenylsulfonyl 1,3-Dienes to Indoles

An efficient synthesis of the antitumor alkaloids ellipticine and olivacine, starting from indole, was developed.The cycloaddition of 3-(phenylsulfonyl)-2,4-hexadiene or 2-(phenylsulfonyl)-1,3-pentadiene to the magnesium salt of indole was followed by C-C