2,5,8,10,13-Pentazapentadec-8-enoic acid, 14-(4,4-dimethyl-2,6-dioxocyclohexylidene)-3-[3-(1,1-dimethylethoxy)-3- oxopropyl]-9-[[(4-methylphenyl)sulfonyl]amino]-4-oxo-15-phenyl-, 9H-fluoren-9-ylmethyl ester, (3S)-

Base Information

Chemical Name:2,5,8,10,13-Pentazapentadec-8-enoic acid, 14-(4,4-dimethyl-2,6-dioxocyclohexylidene)-3-[3-(1,1-dimethylethoxy)-3- oxopropyl]-9-[[(4-methylphenyl)sulfonyl]amino]-4-oxo-15-phenyl-, 9H-fluoren-9-ylmethyl ester, (3S)-
CAS No.:879880-72-5
Molecular Formula:C52H62N6O9S
Molecular Weight:947.165
Hs Code.:

2,5,8,10,13-Pentazapentadec-8-enoic acid,
14-(4,4-dimethyl-2,6-dioxocyclohexylidene)-3-[3-(1,1-dimethylethoxy)-3-
oxopropyl]-9-[[(4-methylphenyl)sulfonyl]amino]-4-oxo-15-phenyl-,
9H-fluoren-9-ylmethyl ester, (3S)-

Synonyms:

Suppliers and Price of 2,5,8,10,13-Pentazapentadec-8-enoic acid, 14-(4,4-dimethyl-2,6-dioxocyclohexylidene)-3-[3-(1,1-dimethylethoxy)-3- oxopropyl]-9-[[(4-methylphenyl)sulfonyl]amino]-4-oxo-15-phenyl-, 9H-fluoren-9-ylmethyl ester, (3S)-

Supply Marketing:

Business phase:: The product has achieved commercial mass production^*data from LookChem market partment

Manufacturers and distributors:

Manufacture/Brand
Chemicals and raw materials
Packaging
price

Total 0 raw suppliers

Chemical Property of 2,5,8,10,13-Pentazapentadec-8-enoic acid, 14-(4,4-dimethyl-2,6-dioxocyclohexylidene)-3-[3-(1,1-dimethylethoxy)-3- oxopropyl]-9-[[(4-methylphenyl)sulfonyl]amino]-4-oxo-15-phenyl-, 9H-fluoren-9-ylmethyl ester, (3S)-

Chemical Property:

Purity/Quality:

Safty Information:

Pictogram(s):
Hazard Codes:

MSDS Files:

Useful:

Technology Process of 2,5,8,10,13-Pentazapentadec-8-enoic acid, 14-(4,4-dimethyl-2,6-dioxocyclohexylidene)-3-[3-(1,1-dimethylethoxy)-3- oxopropyl]-9-[[(4-methylphenyl)sulfonyl]amino]-4-oxo-15-phenyl-, 9H-fluoren-9-ylmethyl ester, (3S)-

There total 5 articles about 2,5,8,10,13-Pentazapentadec-8-enoic acid, 14-(4,4-dimethyl-2,6-dioxocyclohexylidene)-3-[3-(1,1-dimethylethoxy)-3- oxopropyl]-9-[[(4-methylphenyl)sulfonyl]amino]-4-oxo-15-phenyl-, 9H-fluoren-9-ylmethyl ester, (3S)- which guide to synthetic route it. The literature collected by LookChem mainly comes from the sharing of users and the free literature resources found by Internet computing technology. We keep the original model of the professional version of literature to make it easier and faster for users to retrieve and use. At the same time, we analyze and calculate the most feasible synthesis route with the highest yield for your reference as below:

synthetic route:

Reference yield:

: N-[1-(2-Amino-ethylamino)-1-{2-[1-(4,4-dimethyl-2,6-dioxo-cyclohexylidene)-2-phenyl-ethylamino]-ethylamino}-meth-(Z)-ylidene]-4-methyl-benzenesulfonamide

: 71989-18-9
Fmoc-Glu(OtBu)-OH

: 879880-72-5
4-{2-{{{2-[1-(4,4-dimethyl-2,6-dioxo-cyclohexylidene)-2-phenylethylamino]ethylamino}(toluene-4-sulfonylimino)methyl}amino}ethylcarbamoyl}-4-(9H-fluoren-9-ylmethoxycarbonylamino)butyric acid tert-butyl ester

Guidance literature:: With benzotriazol-1-ol; N-(3-dimethylaminopropyl)-N-ethylcarbodiimide; N-ethyl-N,N-diisopropylamine; In dichloromethane; at 20 ℃; for 36h;
DOI:10.1002/chem.200500876

Reference yield:

: 879880-71-4
(2-{[{2-[1-(4,4-dimethyl-2,6-dioxo-cyclohexylidene)-2-phenyl-ethylamino]-ethylamino}-(toluene-4-sulfonylimino)-methyl]-amino}-ethyl)-carbamic acid tert-butyl ester

: 879880-72-5
4-{2-{{{2-[1-(4,4-dimethyl-2,6-dioxo-cyclohexylidene)-2-phenylethylamino]ethylamino}(toluene-4-sulfonylimino)methyl}amino}ethylcarbamoyl}-4-(9H-fluoren-9-ylmethoxycarbonylamino)butyric acid tert-butyl ester

Guidance literature:: Multi-step reaction with 2 steps

1: trifluoroacetic acid / CH₂Cl₂ / 3 h / 20 °C

2: 510 mg / EDC; HOBt; DIPEA / CH₂Cl₂ / 36 h / 20 °C

With benzotriazol-1-ol; N-(3-dimethylaminopropyl)-N-ethylcarbodiimide; N-ethyl-N,N-diisopropylamine; trifluoroacetic acid; In dichloromethane;
DOI:10.1002/chem.200500876

Reference yield:

: C₂₇H₄₁N₄O₄S⁽¹⁺⁾*F₆P^(1-)

: 879880-72-5
4-{2-{{{2-[1-(4,4-dimethyl-2,6-dioxo-cyclohexylidene)-2-phenylethylamino]ethylamino}(toluene-4-sulfonylimino)methyl}amino}ethylcarbamoyl}-4-(9H-fluoren-9-ylmethoxycarbonylamino)butyric acid tert-butyl ester

Guidance literature:: Multi-step reaction with 3 steps

1: DBU / toluene; CHCl₃ / Heating

2: trifluoroacetic acid / CH₂Cl₂ / 3 h / 20 °C

3: 510 mg / EDC; HOBt; DIPEA / CH₂Cl₂ / 36 h / 20 °C

With benzotriazol-1-ol; N-(3-dimethylaminopropyl)-N-ethylcarbodiimide; 1,8-diazabicyclo[5.4.0]undec-7-ene; N-ethyl-N,N-diisopropylamine; trifluoroacetic acid; In dichloromethane; chloroform; toluene;
DOI:10.1002/chem.200500876