5-Cchph

Base Information

Chemical Name:5-Cchph
CAS No.:98350-46-0
Molecular Formula:C₁₉H₃₄N₂O₄
Molecular Weight:354.49
Hs Code.:
DSSTox Substance ID:DTXSID10913319

Synonyms:5-(6-carboxyhexyl)-1-(3-cyclohexane-3-hydroxypropyl)-5-deoxyhydantoin;5-(6-carboxyhexyl)-1-(3-cyclohexane-3-hydroxypropyl)-5-deoxyhydantoin, (2:R*,S* 3:(+-)) isomer;5-CCHPH

Suppliers and Price of 5-Cchph

Supply Marketing:

Business phase:: The product has achieved commercial mass production^*data from LookChem market partment

Manufacturers and distributors:

Manufacture/Brand
Chemicals and raw materials
Packaging
price

Total 3 raw suppliers

Chemical Property of 5-Cchph

Chemical Property:

Vapor Pressure:1.86E-17mmHg at 25°C
Boiling Point:610.5°Cat760mmHg
Flash Point:323°C
PSA：89.87000
Density:1.11g/cm³
LogP:3.40340
XLogP3:3.2
Hydrogen Bond Donor Count:3
Hydrogen Bond Acceptor Count:4
Rotatable Bond Count:11
Exact Mass:354.25185757
Heavy Atom Count:25
Complexity:424

Purity/Quality:

Safty Information:

Pictogram(s):
Hazard Codes:

MSDS Files:

Useful:

Canonical SMILES:C1CCC(CC1)C(CCN2C(CNC2=O)CCCCCCC(=O)O)O
Isomeric SMILES:C1CCC(CC1)[C@@H](CCN2C(CNC2=O)CCCCCCC(=O)O)O

Technology Process of 5-Cchph

There total 16 articles about 5-Cchph which guide to synthetic route it. The literature collected by LookChem mainly comes from the sharing of users and the free literature resources found by Internet computing technology. We keep the original model of the professional version of literature to make it easier and faster for users to retrieve and use. At the same time, we analyze and calculate the most feasible synthesis route with the highest yield for your reference as below:

synthetic route:

Reference yield: 55.0%

: 136494-30-9,136494-31-0
7-[(R)-1-Benzyl-3-((S)-3-cyclohexyl-3-hydroxy-propyl)-2-oxo-imidazolidin-4-yl]-heptanoic acid

: 98350-46-0,98350-53-9
(+/-)-(S^*,R^*)-3-(3-cyclohexyl-3-hydroxypropyl)-2-oxo-4-imidazolidineheptanoic acid

Guidance literature:: With ammonia; sodium; In tetrahydrofuran; Heating;
DOI:10.1002/ardp.2503240802

Reference yield: 41.0%

: 136494-30-9,136494-31-0
7-[(R)-1-Benzyl-3-((R)-3-cyclohexyl-3-hydroxy-propyl)-2-oxo-imidazolidin-4-yl]-heptanoic acid

: 98350-46-0,98350-53-9
(+/-)-(S^*,S^*)-3-(3-cyclohexyl-3-hydroxypropyl)-2-oxo-4-imidazolidineheptanoic acid

Guidance literature:: With ammonia; sodium; In tetrahydrofuran; Heating;
DOI:10.1002/ardp.2503240802

Reference yield:

: 65706-29-8
diethyl 2-(3-cyclohexyl-3-hydroxypropyl)aminononanedioate

: 98350-46-0,98350-53-9
(+/-)-(S^*,R^*)-3-(3-cyclohexyl-3-hydroxypropyl)-2-oxo-4-imidazolidineheptanoic acid

Guidance literature:: Multi-step reaction with 6 steps

1: toluene / 2 h / Ambient temperature

2: 1,8-diazabicyclo<5.4.0>undec-7-ene / toluene / 1.) room temp., 16 h 2.) 60 deg C, 1 h

3: 56 percent / NaBH₄, acetic acid / propan-2-ol / 1.) 3 h 2.) room temp., overnight

4: water, K₂CO₃ / methanol / 1 h / Heating

5: 60 percent / Na, NH₃ (liquid) / tetrahydrofuran / 1 h / Heating

6: 1.) trifluoroacetic acid, triethylsilane 2.) water, K₂CO₃ / 1a) 50 deg C, 8 h 1b) 50 deg C, 3 h 2.) methanol, room temp., overnight

With triethylsilane; sodium tetrahydroborate; ammonia; water; sodium; potassium carbonate; acetic acid; 1,8-diazabicyclo[5.4.0]undec-7-ene; trifluoroacetic acid; In tetrahydrofuran; methanol; isopropyl alcohol; toluene;
DOI:10.1002/ardp.2503240802